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Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Trimethoprim and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Trimethoprim impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Trimethoprim-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

N-Nitroso Trimethoprim Impurity A
CAT No: CL-TOP-NO-01 CAS No: NA Mol Wt: 333.34 Mol F: C15H19N5O4 Inv Status: Custom Synthesis
Chemical Name: N-(4-amino-5-(3,4,5-trimethoxybenzyl)pyrimidin-2-yl)-N-methylnitrous amide
N-Nitroso Trimethoprim Impurity I
CAT No: CL-TOP-NO-02 CAS No: NA Mol Wt: 353.38 Mol F: C19H19N3O4 Inv Status: Custom Synthesis
Chemical Name: (Z)-N-(2-cyano-3-(3,4,5-trimethoxyphenyl)prop-1-en-1-yl)-N-phenylnitrous amide
N-Nitroso Trimethoprim Impurity 1
CAT No: CL-TOP-NO-03 CAS No: NA Mol Wt: 333.34 Mol F: C15H19N5O4 Inv Status: Custom Synthesis
Chemical Name: N-(2-amino-5-(3,4,5-trimethoxybenzyl)pyrimidin-4-yl)-N-methylnitrous amide
N-Nitroso Trimethoprim Impurity 2
CAT No: CL-TOP-NO-04 CAS No: NA Mol Wt: 291.3 Mol F: C14H17N3O4 Inv Status: Custom Synthesis
Chemical Name: (Z)-N-(2-cyano-3-(3,4,5-trimethoxyphenyl)prop-1-en-1-yl)-N-methylnitrous amide
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