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Ketorolac is a potent NSAID used primarily for short-term management of moderate to severe pain, often after surgery. It works by inhibiting prostaglandin synthesis via COX enzyme blockade, providing analgesic and anti-inflammatory effects. Due to its potential for gastrointestinal, renal, and bleeding complications, it is typically prescribed for no more than 5 days and is not recommended for chronic pain management.
Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Ketotifen and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Ketotifen impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Ketotifen-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

N-Nitroso ketotifen Impurity
CAT No: CL-KTF-NO-01 CAS No: NA Mol Wt: 324.4 Mol F: C18H16N2O2S Inv Status: Custom Synthesis
Chemical Name: 4-(1-nitrosopiperidin-4-ylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one
N-Nitroso ketotifen Impurity A
CAT No: CL-KTF-NO-02 CAS No: NA Mol Wt: 308.4 Mol F: : C18H16N2OS Inv Status: Custom Synthesis
Chemical Name: 4-(4h-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-nitrosopiperidine
N-Nitroso ketotifen Impurity C
CAT No: CL-KTF-NO-03 CAS No: NA Mol Wt: 342.41 Mol F: C18H18N2O3S Inv Status: Custom Synthesis
Chemical Name: 4(r)-4-hydroxy-4-(1-nitrosopiperidin-4-yl)-4h-benzo[4,5]cyclohepta[1,2-b]thiophen-10(9h)-one
N-Nitroso ketotifen Impurity E
CAT No: CL-KTF-NO-04 CAS No: NA Mol Wt: 324.4 Mol F: C18H16N2O2S Inv Status: Custom Synthesis
Chemical Name: 10-(1-nitrosopiperidin-4-ylidene)-5,10-dihydro-4h-benzo[5,6]cyclohepta[1,2-b]thiophen-4-one
N-Nitroso ketotifen Impurity G
CAT No: CL-KTF-NO-05 CAS No: NA Mol Wt: 338.38 Mol F: C18H14N2O3S Inv Status: Custom Synthesis
Chemical Name: 4-(1-nitrosopiperidin-4-ylidene)-4h-benzo[4,5]cyclohepta[1,2-b]thiophene-9,10-dione
N-Nitroso ketotifen Impurity B
CAT No: CL-KTF-NO-06 CAS No: NA Mol Wt: 356.44 Mol F:  C19H20N2O3S Inv Status: Custom Synthesis
Chemical Name: (R)-10-methoxy-4-(1-nitrosopiperidin-4-yl)-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ol
N-Nitroso ketotifen Impurity 1
CAT No: CL-KTF-NO-07 CAS No: NA Mol Wt: 148.59 Mol F: C5H9ClN2O Inv Status: Custom Synthesis
Chemical Name: 4-chloro-1-nitrosopiperidine
N-Nitroso ketotifen Impurity 2
CAT No: CL-KTF-NO-08 CAS No: NA Mol Wt: 326.41 Mol F:  C18H18N2O2S Inv Status: Custom Synthesis
Chemical Name: 4-(1-nitrosopiperidin-4-yl)-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ol
N-Nitroso ketotifen Impurity F
CAT No: CL-KTF-NO-09 CAS No: NA Mol Wt: 324.4 Mol F: C18H16N2O2S Inv Status: Custom Synthesis
Chemical Name: 4-(1-nitrosopiperidin-4-ylidene)-4h-benzo[4,5]cyclohepta[1,2-b]thiophen-9(10h)-one
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