Icatibant is a selective bradykinin B2 receptor antagonist used to treat hereditary angioedema (HAE). By blocking the action of bradykinin, a peptide involved in inflammatory responses, it reduces the frequency and severity of swelling episodes. It is typically administered subcutaneously during acute attacks of HAE.
Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Icatibant and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Icatibant impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Icatibant-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.
Chemical Name: ((2s,3as,7as)-1-((r)-2-(((s)-2-(2-((2s,4r)-4-hydroxy-1-(nd-Nitroso-d-arginyl-l-arginyl-l-prolyl)pyrrolidine-2-carboxamido)acetamido)-3-(thiophen-2-yl)propanoyl)-l-seryl)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)octahydro-1h-indole-2-carbonyl)-l-arginine
Chemical Name: ((2s,3as,7as)-1-((r)-2-(((s)-2-(2-((2s,4r)-4-hydroxy-1-(nd-Nitroso-n2-(nd-Nitroso-d-arginyl)-l-arginyl-l-prolyl)pyrrolidine-2-carboxamido)acetamido)-3-(thiophen-2-yl)propanoyl)-l-seryl)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)octahydro-1h-indole-2-carbonyl)-l-arginine
Chemical Name: (6s,9s,12s)-12-(3-guanidino-4-oxo-4-(1,2,3,4-tetrahydroisoquinolin-3-yl)butyl)-1-((2s)-4-hydroxy-1-(nd-Nitroso-l-arginyl-l-prolyl)pyrrolidin-2-yl)-9-(hydroxymethyl)-11-((2s,3as,7ar)-octahydro-1h-indole-2-carbonyl)-1,4,7,10-tetraoxo-6-(thiophen-2-ylmethyl)-2,5,8,11-tetraazatridecan-13-oic acid
Chemical Name: ((2s,3as,7as)-1-((r)-2-(((s)-2-(2-((2s,4r)-4-hydroxy-1-(nd-Nitroso-d-arginyl-l-arginyl-l-prolyl)pyrrolidine-2-carboxamido)acetamido)-3-(thiophen-2-yl)propanoyl)-l-seryl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)octahydro-1h-indole-2-carbonyl)-l-arginine
Chemical Name: ((2s,3as,7as)-1-((3s,6r)-3-((s)-2-(2-((2r,4r)-1-(n2-(d-arginyl)-nd-Nitroso-l-arginyl-l-prolyl)-4-hydroxypyrrolidine-2-carboxamido)acetamido)-3-(thiophen-2-yl)propanamido)-4-oxo-3,4,7,11b-tetrahydro-2h,6h-[1,3]oxazino[2,3-a]isoquinoline-6-carbonyl)octahydro-1h-indole-2-carbonyl)-l-arginine
Chemical Name: (2s)-5-((diaminomethylene)amino)-2-((3as,7as)-1-(2-(((2s)-2-(2-((4r)-1-((5-((diaminomethylene)amino)-2-((r)-4-(3-((diaminomethylene)amino)propyl)-3-Nitroso-5-oxoimidazolidin-1-yl)pentanoyl)-l-prolyl)-4-hydroxypyrrolidine-2-carboxamido)acetamido)-3-(thiophen-2-yl)propanoyl)-l-seryl)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)octahydro-1h-indole-2-carboxamido)pentanoic acid
Chemical Name: N2-((2s,3as,7as)-1-((r)-2-(((s)-2-(2-((2s,4r)-4-hydroxy-1-(nd-Nitroso-d-arginyl-l-arginyl-l-prolyl)pyrrolidine-2-carboxamido)acetamido)-3-(thiophen-2-yl)propanoyl)-l-seryl)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)octahydro-1h-indole-2-carbonyl)-nd-Nitroso-l-arginine
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