Icatibant is a selective bradykinin B2 receptor antagonist used to treat hereditary angioedema (HAE). By blocking the action of bradykinin, a peptide involved in inflammatory responses, it reduces the frequency and severity of swelling episodes. It is typically administered subcutaneously during acute attacks of HAE.
Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Icatibant and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Icatibant impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Icatibant-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.