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Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Ergotamine and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Ergotamine impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Ergotamine-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

N-Nitroso Ergotamine Impurity 1
CAT No: CL-EGM-NO-001 CAS No: NA Mol Wt: 626.7 Mol F: C33H34N6O7 Inv Status: Custom Synthesis
Chemical Name: (6aR,9S)-N-((2R,5S,10aS,10bS)-5-benzyl-10b-hydroxy-2-methyl-3,6-dioxooctahydro-2H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-9-hydroxy-7-methyl-N-nitroso-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
N-Nitroso Ergotamine Impurity 2
CAT No: CL-EGM-NO-002 CAS No: NA Mol Wt: 626.7 Mol F: C33H34N6O7 Inv Status: Custom Synthesis
Chemical Name: (6aR,9S)-N-((2R,5S,10aS,10bS)-5-benzyl-10b-hydroxy-2-methyl-3,6-dioxooctahydro-2H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-9-hydroxy-7-methyl-4-nitroso-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
N-Nitroso Ergotamine
CAT No: CL-EGM-NO-003 CAS No: NA Mol Wt: 612.6 Mol F: C32H32N6O7 Inv Status: Custom Synthesis
Chemical Name: (6aR,9S)-N-((2R,5S,10aS,10bS)-5-benzyl-10b-hydroxy-2-methyl-3,6-dioxooctahydro-2H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-9-hydroxy-7-nitroso-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
N-Nitroso Ergotamine Impurity A
CAT No: CL-EGM-NO-004 CAS No: NA Mol Wt: 641.6 Mol F: C32H31N7O8 Inv Status: Custom Synthesis
Chemical Name: (6aR,9S)-N-((2R,5S,10aS,10bS)-5-benzyl-10b-hydroxy-2-methyl-3,6-dioxooctahydro-2H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-9-hydroxy-4,7-dinitroso-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
N-Nitroso Ergotamine Impurity B
CAT No: CL-EGM-NO-005 CAS No: NA Mol Wt: 596.6 Mol F: C32H32N6O6 Inv Status: Custom Synthesis
Chemical Name: (6aR,9S)-N-((2R,5S,10aS,10bS)-5-benzyl-10b-hydroxy-2-methyl-3,6-dioxooctahydro-2H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-7-nitroso-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
N-Nitroso Ergotamine Impurity 3
CAT No: CL-EGM-NO-006 CAS No: NA Mol Wt: 596.6 Mol F: C32H32N6O6 Inv Status: Custom Synthesis
Chemical Name: (6aR,9S)-N-((2R,5S,10aS,10bS)-5-benzyl-10b-hydroxy-2-methyl-3,6-dioxooctahydro-2H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-4-nitroso-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
N-Nitroso Ergotamine Impurity 4
CAT No: CL-EGM-NO-007 CAS No: NA Mol Wt: 610.7 Mol F: C33H34N6O6 Inv Status: Custom Synthesis
Chemical Name: (6aR,9R)-N-((2R,5S,10aS,10bS)-5-benzyl-2-ethyl-10b-hydroxy-3,6-dioxooctahydro-2H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-7-nitroso-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
N-Nitroso Ergotamine Impurity D
CAT No: CL-EGM-NO-008 CAS No: NA Mol Wt: 624.7 Mol F: C34H36N6O6 Inv Status: Custom Synthesis
Chemical Name: (6aR,9R)-N-((2R,5S,10aS,10bS)-5-benzyl-10b-hydroxy-2-isopropyl-3,6-dioxooctahydro-2H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-7-nitroso-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
N-Nitroso Ergotamine Impurity 5
CAT No: CL-EGM-NO-009 CAS No: NA Mol Wt: 638.7 Mol F: C35H38N6O6 Inv Status: Custom Synthesis
Chemical Name: (6aR,9R)-N-((2R,5S,10aS,10bS)-5-benzyl-10b-hydroxy-2-isopropyl-3,6-dioxooctahydro-2H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-7-methyl-4-nitroso-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
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