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Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Vardenafil and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Vardenafil impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Vardenafil-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

Vardenafil Hydrochloride Trihydrate

CAT No: CL-VDF-01 CAS No: 330808-88-3 Mol Wt: 488.6 : 36.5 : 3(18.0) Mol F: C23H32N6O4S : HCl : 3H2O Inv Status: Custom Synthesis

Chemical Name: 2-(2-Ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one hydrochloride trihydrate

Vardenafil Dihydrochloride

CAT No: CL-VDF-02 CAS No: 224789-15-5 Mol Wt: 488.6 : 2(36.5) Mol F: C23H32N6O4S : 2(HCl) Inv Status: Custom Synthesis

Chemical Name: 1-[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-ethyl-piperazine dihydrochloride

Vardenafil Carboxylic Acid Impurity

CAT No: CL-VDF-03 CAS No: 358390-39-3 Mol Wt: 356.4 Mol F: C18H20N4O4 Inv Status: Custom Synthesis

Chemical Name: 3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxybenzoic acid

Vardenafil Chlorosulfone Impurity

CAT No: CL-VDF-04 CAS No: 224789-26-8 Mol Wt: 410.9 Mol F: C17H19CIN4O4S Inv Status: Custom Synthesis

Chemical Name: 4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydro-imidazo[5,1-f][1,2,4]-triazin-2-yl)benzenesulfonyl chloride

Vardenafil EP Impurity B

CAT No: CL-VDF-05 CAS No: 437717-43-6 Mol Wt: 392.4 Mol F: C17H20N4O5S Inv Status: Custom Synthesis

Chemical Name: 4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonic ac

Vardenafil Dessulfonyl Impurity

CAT No: CL-VDF-06 CAS No: 224789-21-3 Mol Wt: 312.4 Mol F: C17H20N4O2 Inv Status: Custom Synthesis

Chemical Name: 2-(2-Ethoxyphenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one

Vardenafil Hydroxy Impurity

CAT No: CL-VDF-07 CAS No: 224785-98-2 Mol Wt: 504.6 Mol F: C23H32N6O5S Inv Status: Custom Synthesis

Chemical Name: 1-[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-hydroxyethyl-piperazine

Vardenafil Hydroxy Thione Impurity

CAT No: CL-VDF-08 CAS No: 912576-30-8 Mol Wt: 520.7 Mol F: C23H32N6O4S2 Inv Status: Custom Synthesis

Chemical Name: 2-[2-Ethoxy-5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]phenyl]-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazine-4(1H)-thione

Vardenafil Related Compound E

CAT No: CL-VDF-09 CAS No: 448184-46-1 Mol Wt: 460.6 Mol F: C21H28N6O4S Inv Status: Custom Synthesis

Chemical Name: 1-[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-piperazine

Vardenafil EP Impurity C

CAT No: CL-VDF-10 CAS No: 1255919-03-9 Mol Wt: 834.9 Mol F: C38H46N10O8S2 Inv Status: Custom Synthesis

Chemical Name: 2,2'-((Piperazine-1,4-disulfonyl)bis(2-ethoxy-5,1-phenylene))bis(5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one)

Pseudo Vardenafil

CAT No: CL-VDF-11 CAS No: 224788-34-5 Mol Wt: 459.6 Mol F: C22H29N5O4S Inv Status: Custom Synthesis

Chemical Name: Piperidine, 1-[[3-(1,4-dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]- (9CI) 2-[2-Ethoxy-5-(1-piperidinylsulfonyl)phenyl]-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one

Vardenafil HCl

CAT No: CL-VDF-12 CAS No: 224785-91-5 Mol Wt: 488.6 : 36.5 Mol F: C23H32N6O4S : HCl Inv Status: Custom Synthesis

Chemical Name: 2-(2-Ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride

Vardenafil Benzoyl Impurity

CAT No: CL-VDF-13 CAS No: 1255919-01-7 Mol Wt: 522.6 Mol F: C26H30N6O4S Inv Status: Custom Synthesis

Chemical Name: 2-(2-ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-phenylimidazo[5,1-f][1,2,4]triazin-4(1H)-one

Acetyl Vardenafil

CAT No: CL-VDF-14 CAS No: 1261351-28-3 Mol Wt: 466.6 Mol F: C25H34N6O3 Inv Status: Custom Synthesis

Chemical Name: 2-(2-ethoxy-5-(2-(4-ethylpiperazin-1-yl)acetyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one

Vardenafil Impurity (2-Ethoxy-N-Hydroxy Benzamidine)

CAT No: CL-VDF-15 CAS No: 879-57-2 Mol Wt: 180.2 Mol F: C9H12N2O2 Inv Status: Custom Synthesis

Chemical Name: 2-Ethoxy-N-hydroxybenzenecarboximidamide

Vardenafil Impurity (2-Ethoxy Benzamidine Hydrochloride)

CAT No: CL-VDF-16 CAS No: 18637-00-8 Mol Wt: 164.2 : 36.5 Mol F: C9H12N2O : HCl Inv Status: Custom Synthesis

Chemical Name: 2-Ethoxybenzamidine hydrochloride

Vardenafil Oxopiperazine

CAT No: CL-VDF-17 CAS No: 448184-58-5 Mol Wt: 474.5 Mol F: C21H26N6O5S Inv Status: Custom Synthesis

Chemical Name: 2-[2-Ethoxy-5-[(3-oxo-1-piperazinyl)sulfonyl]phenyl]-5-methyl-7-propyl-imidazo[5,1-f][1,2,4]triazin-4(1H)-one; 4-[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-piperazinone

Vardenafil Acetyl Analogue

CAT No: CL-VDF-18 CAS No: NA Mol Wt: 437.6 Mol F: C24H31N5O3 Inv Status: Custom Synthesis

Chemical Name: 2-(2-Ethoxy-5-(2-(piperidin-1-yl)acetyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one

Vardenafil USP Related Compound D

CAT No: CL-VDF-19 CAS No: 448184-48-3 Mol Wt: 504.6 Mol F: C23H32N6O5S Inv Status: Custom Synthesis

Chemical Name: 4-((4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-1,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)phenyl)sulfonyl)-1-ethylpiperazine 1-oxide

N-Desethyl-N-Methyl Vardenafil

CAT No: CL-VDF-20 CAS No: 224785-87-9 Mol Wt: 474.6 Mol F: C22H30N6O4S Inv Status: Custom Synthesis

Chemical Name: 1-[[3-(1,4-dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-methyl- (9CI)2-[2-Ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one

O-Desethyl Vardenafil

CAT No: CL-VDF-21 CAS No: 2411340-39-9 Mol Wt: 460.6 Mol F: C21H28N6O4S Inv Status: Custom Synthesis

Chemical Name: 2-(5-((4-Ethylpiperazin-1-yl)sulfonyl)-2-hydroxyphenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one

Vardenafil Impurity 1

CAT No: CL-VDF-22 CAS No: 1417529-67-9 Mol Wt: 342.4 Mol F: C17H18N4O4 Inv Status: Custom Synthesis

Chemical Name: Ethyl 2-(2-ethoxyphenyl)-5-methyl-4-oxo-3,4-dihydroimidazo[5,1-f][1,2,4]triazine-7-carboxylate

Vardenafil Impurity 2

CAT No: CL-VDF-23 CAS No: 1417529-69-1 Mol Wt: 518.6 Mol F: C23H30N6O6S Inv Status: Custom Synthesis

Chemical Name: Ethyl 2-[2-ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-1,4-dihydro-5-methyl-4-oxoimidazo[5,1-f][1,2,4]triazine-7-carboxylate

Vardenafil EP Impurity A

CAT No: CL-VDF-24 CAS No: 2169247-39-4 Mol Wt: 460.6 Mol F: C21H28N6O4S Inv Status: Custom Synthesis

Chemical Name: 2-(2-Ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5,7-dimethylimidazo[5,1-f][1,2,4]triazin-4(3H)-one

Vardenafil Impurity 4

CAT No: CL-VDF-25 CAS No: 448184-56-3 Mol Wt: 506.5 Mol F: C21H26N6O7S Inv Status: Custom Synthesis

Chemical Name: [[2-[[[3-(1,4-dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]amino]ethyl]amino]oxo- (9CI) 2-[[2-[[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]amino]ethyl]amino]-2-oxoacetic acid

Vardenafil Impurity 5

CAT No: CL-VDF-26 CAS No: 927690-90-2 Mol Wt: 330.4 Mol F: C17H22N4O3 Inv Status: Custom Synthesis

Chemical Name: N-(1-(3-(2-Ethoxyphenyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)ethyl)butyramide

Vardenafil Impurity 6

CAT No: CL-VDF-27 CAS No: NA Mol Wt: 498.7 Mol F: C25H34N6OS2 Inv Status: Custom Synthesis

Chemical Name: 2-(2-Ethoxy-5-((3R,5S)-3,4,5-trimethylpiperazine-1-carbonothioyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazine-4(3H)-thione

Vardenafil Impurity 7

CAT No: CL-VDF-28 CAS No: 5308-25-8 Mol Wt: 114.2 Mol F: C6H14N2 Inv Status: Custom Synthesis

Chemical Name: 1-Ethylpiperazine

Vardenafil Impurity 8

CAT No: CL-VDF-29 CAS No: NA Mol Wt: 504.6 Mol F: C23H32N6O5S Inv Status: Custom Synthesis

Chemical Name: (1-Ethyl-4-{4-ethoxy-3-[5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl]benzenesulfonyl}piperazine N-oxide)

Vardenafil Impurity 9

CAT No: CL-VDF-30 CAS No: NA Mol Wt: 328.3 Mol F: C16H16N4O4 Inv Status: Custom Synthesis

Chemical Name: Methyl 2-(2-ethoxyphenyl)-5-methyl-4-oxo-3,4-dihydroimidazo[5,1-f][1,2,4]triazine-7-carboxylate

Vardenafil Impurity 10

CAT No: CL-VDF-31 CAS No: 1169861-36-2 Mol Wt: 355.5 Mol F: C15H25N5O3S Inv Status: Custom Synthesis

Chemical Name: 2-Ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)benzimidohydrazide

Vardenafil Di Ester Impurity (Z isomer)

CAT No: CL-VDF-32 CAS No: 75435-43-7 Mol Wt: 315.3 Mol F: C14H21NO7 Inv Status: Custom Synthesis

Chemical Name: (Z)-3-Butyramido-1-ethoxy-1-oxobut-2-en-2-yl ethyl oxalate

2-Ethoxybenzimidohydrazide

CAT No: CL-VDF-35 CAS No: 889943-46-8 Mol Wt: 179.2 Mol F: C9H13N3O Inv Status: Custom Synthesis

Chemical Name: 2-Ethoxybenzimidohydrazide

Type:Impurity Reference Standard

Total Products: 33

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