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Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Trazodone and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Trazodone impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Trazodone-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

Trazodone Hydrochloride

CAT No: CL-TRZ-01 CAS No: 25332-39-2 ; 19794-93-5 (free base) Mol Wt: 371.9 : 36.5 Mol F: C19H22ClN5O : HCl Inv Status: In Stock

Chemical Name: 2-[3-[4-(3-Chlorophenyl)piperazin-1-yl]propyl][1,2,4]triazolo[4,3-a]pyridin-3(2H)-one hydrochloride ; 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-, monohydrochloride (as per USP)

Trazodone EP Impurity A

CAT No: CL-TRZ-02 CAS No: 55290-68-1 ; 55290-66-9 (HCl salt) Mol Wt: 387.9 Mol F: C19H22ClN5O2 Inv Status: In Stock

Chemical Name: 4-(3-chlorophenyl)-1-[3-(3-oxo-2,3-dihydro[1,2,4]triazolo[4,3-a]pyridin-2-yl)propyl]piperazine 1-oxide ; 4-(3-Chlorophenyl)-1-[3-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl]piperazine 1-oxide (as per USP)

Trazodone EP Impurity C

CAT No: CL-TRZ-03 CAS No: 157072-19-0 Mol Wt: 371.9 Mol F: C19H22ClN5O Inv Status: In Stock

Chemical Name: 2-[3-[4-(4-chlorophenyl)piperazin-1-yl]propyl][1,2,4]triazolo[4,3-a]pyridin-3(2H)-one (as per EP & USP)

Trazodone EP Impurity D (HCl)

CAT No: CL-TRZ-04 CAS No: 1263278-80-3 ; 1263358-13-9 (free base) Mol Wt: 416.3 : 36.5 Mol F: C19H22BrN5O : HCl Inv Status: In Stock

Chemical Name: 2-[3-[4-(3-bromophenyl)piperazin-1-yl]propyl][1,2,4]triazolo[4,3-a]pyridin-3(2H)-one hydrochloride (as per EP & USP)

Trazodone EP Impurity E

CAT No: CL-TRZ-05 CAS No: 1346599-35-6 Mol Wt: 399.9 Mol F: C21H26ClN5O Inv Status: Custom Synthesis

Chemical Name: 2-[3-[4-(3-chloro-4-ethylphenyl)piperazin-1-yl]propyl][1,2,4]triazolo[4,3-a]pyridin-3(2H)-one (as per EP & USP)

Trazodone EP Impurity G (HCl)

CAT No: CL-TRZ-06 CAS No: 2470441-00-8 ; 2470436-00-9 (free base) Mol Wt: 310.9 : 36.5 Mol F: C17H27ClN2O : HCl Inv Status: In Stock

Chemical Name: 1-(3-chlorophenyl)-4-[3-(2-methylpropoxy)propyl]piperazine hydrochloride ; 1-(3-Chlorophenyl)-4-(3-isobutoxypropyl)piperazine (as per USP)

Trazodone EP Impurity B

CAT No: CL-TRZ-07 CAS No: 62337-66-0 Mol Wt: 337.4 Mol F: C19H23N5O Inv Status: In Stock

Chemical Name: 2-[3-(4-phenylpiperazin-1-yl)propyl][1,2,4]triazolo[4,3-a]pyridin-3(2H)-one ; 2-[3-(4-Phenylpiperazin-1-yl)propyl]-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one (as per USP)

Trazodone EP Impurity J (HCl)

CAT No: CL-TRZ-08 CAS No: 1263278-79-0 ; 1263358-12-8 (free base) Mol Wt: 406.3 : 36.5 Mol F: C19H21Cl2N5O : HCl Inv Status: In Stock

Chemical Name: 2-[3-[4-(3,4-dichlorophenyl)piperazin-1-yl]propyl][1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Trazodone USP Related Compound F (HCl)

CAT No: CL-TRZ-09 CAS No: 52605-52-4 ; 39577-43-0 (free base) Mol Wt: 273.2 : 36.5 Mol F: C13H18Cl2N2 : HCl Inv Status: In Stock

Chemical Name: 1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride (as per USP)

Trazodone Impurity 10

CAT No: CL-TRZ-11 CAS No: NA Mol Wt: 405.9 Mol F: C19H24ClN5O3 Inv Status: Custom Synthesis

Chemical Name: 2-(3-(4-(2-Chlorophenyl)piperazin-1-yl)propyl)-6,7-dihydroxy-2,3a,6,7-tetrahydro-3H-pyrazolo[4,3-b]pyridin-3-one

Trazodone EP Impurity I

CAT No: CL-TRZ-12 CAS No: 32229-98-4 Mol Wt: 254.8 Mol F: C13H19ClN2O Inv Status: In Stock

Chemical Name: 3-[4-(3-chlorophenyl)piperazin-1-yl]propan-1-ol

Trazodone EP Impurity M (HCl)

CAT No: CL-TRZ-13 CAS No: ; 157072-18-9 (free base) Mol Wt: 372.9 : 36.5 Mol F: C19H23ClN5O : HCl Inv Status: In Stock

Chemical Name: (1-(3-(4-(3-Chlorophenyl)piperazin-1-ium-1-yl)propyl)-3-oxo-2,3-dihydro-[1,2,4]triazolo[4,3-a]pyridin-1-ium)chloride hydrochloride

Trazodone Dimer 2

CAT No: CL-TRZ-14 CAS No: ; 2727463-29-6 (free base) Mol Wt: 769.8 : 2(36.5) Mol F: C40H46Cl2N10O2 : 2(HCl) Inv Status: Custom Synthesis

Chemical Name: 2,2'-(((Ethane-1,1-diylbis(3-chloro-4,1-phenylene))bis(piperazine-4,1-diyl))bis(propane-3,1-diyl))bis([1,2,4]triazolo[4,3-a]pyridin-3(2H)-one) dihydrochloride

Trazodone EP Impurity H

CAT No: CL-TRZ-15 CAS No: ?6323-09-7 ; 2408971-27-5 (dihydrochloride salt) Mol Wt: 433.4 Mol F: C23H30Cl2N4 Inv Status: In Stock

Chemical Name: 1,1?-(propane-1,3-diyl)bis[4-(3-chlorophenyl)piperazine]

Trazodone EP Impurity K

CAT No: CL-TRZ-16 CAS No: 6969-71-7 Mol Wt: 135.1 Mol F: C6H5N3O Inv Status: In Stock

Chemical Name: [1,2,4]triazolo[4,3-a]pyridin-3(2H)-one (as per EP & USP)

Trazodone EP Impurity L

CAT No: CL-TRZ-17 CAS No: 6640-24-0 Mol Wt: 196.7 Mol F: C10H13ClN2 Inv Status: Custom Synthesis

Chemical Name: 1-(3-Chlorophenyl)piperazine

Trazodone Impurity E

CAT No: CL-TRZ-18 CAS No: 6323-14-4 Mol Wt: 273.2 Mol F: C13H18Cl2N2 Inv Status: In Stock

Chemical Name: 1-(4-Chlorophenyl)-4-(3-chloropropyl)piperazine

Trazodone Dimeric Impurity

CAT No: CL-TRZ-19 CAS No: NA Mol Wt: 741.7 Mol F: C38H42Cl2N10O2 Inv Status: Custom Synthesis

Chemical Name: 2,2'-(2,3-Bis((4-(3-chlorophenyl)piperazin-1-yl)methyl)butane-1,4-diyl)bis([1,2,4]triazolo[4,3-a]pyridin-3(2H)-one)

Trazodone Impurity 12

CAT No: CL-TRZ-20 CAS No: 2514735-38-5 Mol Wt: 406.3 Mol F: C19H21Cl2N5O Inv Status: Custom Synthesis

Chemical Name: 7-Chloro-2-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Trazodone Impurity L (HCl salt)

CAT No: CL-TRZ-21 CAS No: 13078-15-4 ; 6640-24-0 (free base) Mol Wt: 196.7 : 36.5 Mol F: C10H13ClN2 : HCl Inv Status: Custom Synthesis

Chemical Name: 1-(3-Chlorophenyl)piperazine hydrochloride

Trazodone Impurity 13

CAT No: CL-TRZ-22 CAS No: NA Mol Wt: 345.8 Mol F: C17H20ClN5O Inv Status: Custom Synthesis

Chemical Name: 2-(3-((2-((2-Chlorophenyl)amino)ethyl)amino)propyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Trazodone Impurity 5

CAT No: CL-TRZ-23 CAS No: 55290-67-0 Mol Wt: 405.9 Mol F: C19H24ClN5O3 Inv Status: Custom Synthesis

Chemical Name: 2-(3-(4-(3-Chlorophenyl)piperazin-1-yl)propyl)-7,8-dihydroxy-7,8-dihydro-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Trazodone Impurity 28

CAT No: CL-TRZ-24 CAS No: 220910-13-4 ; 220910-12-3 (free base) Mol Wt: 345.8 : 36.5 Mol F: C17H20ClN5O : HCl Inv Status: Custom Synthesis

Chemical Name: 2-(3-((2-((3-Chlorophenyl)amino)ethyl)amino)propyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one hydrochloride

Trazodone EP Impurity A (HCl)

CAT No: CL-TRZ-25 CAS No: 55290-66-9 ; 55290-68-1 (free base) Mol Wt: 387.9 : 36.5 Mol F: C19H22ClN5O2 : HCl Inv Status: In Stock

Chemical Name: 4-(3-chlorophenyl)-1-[3-(3-oxo-2,3-dihydro[1,2,4]triazolo[4,3-a]pyridin-2-yl)propyl]piperazine 1-oxide hydrochloride ; 4-(3-Chlorophenyl)-1-[3-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl]piperazine 1-oxide hydrochloride (as per USP)

Trazodone EP Impurity C (HCl)

CAT No: CL-TRZ-26 CAS No: 1263278-77-8 ; 157072-19-0 (free base) Mol Wt: 371.9 : 36.5 Mol F: C19H22ClN5O : HCl Inv Status: In Stock

Chemical Name: 2-[3-[4-(4-chlorophenyl)piperazin-1-yl]propyl][1,2,4]triazolo[4,3-a]pyridin-3(2H)-one hydrochloride

Trazodone USP Related Compound F

CAT No: CL-TRZ-27 CAS No: 39577-43-0 ; 52605-52-4 (HCl salt) ; 123733-61-9 (2HCl salt) ; 78118-82-8 (XHBr salt) Mol Wt: 273.2 Mol F: C13H18Cl2N2 Inv Status: In Stock

Chemical Name: 1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine

Trazodone Impurity 29

CAT No: CL-TRZ-28 CAS No: 100-00-5 Mol Wt: 157.6 Mol F: C6H4ClNO2 Inv Status: In Stock

Chemical Name: 1-Chloro-4-nitrobenzene

Trazodone EP Impurity G

CAT No: CL-TRZ-29 CAS No: 2470436-00-9 ; 2470441-00-8 (HCl salt) Mol Wt: 310.9 Mol F: C17H27ClN2O Inv Status: In Stock

Chemical Name: 1-(3-Chlorophenyl)-4-[3-(2-methylpropoxy)propyl]piperazine ; 1-(3-Chlorophenyl)-4-(3-isobutoxypropyl)piperazine (as per USP)

Trazodone Impurity 30

CAT No: CL-TRZ-30 CAS No: 141511-00-4 Mol Wt: 236.7 Mol F: C13H17ClN2 Inv Status: Custom Synthesis

Chemical Name: 1-Allyl-4-(3-chlorophenyl)piperazine

Trazodone Impurity 31

CAT No: CL-TRZ-31 CAS No: NA Mol Wt: 340.8 Mol F: C17H25ClN2O3 Inv Status: Custom Synthesis

Chemical Name: 3-(4-(3-Chlorophenyl)piperazin-1-yl)propyl isopropyl carbonate

Trazodone Impurity 32

CAT No: CL-TRZ-32 CAS No: 53689-10-4 Mol Wt: 317.2 Mol F: C13H18Cl2N4O Inv Status: Custom Synthesis

Chemical Name: 2-(3-(Bis(2-chloroethyl)amino)propyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Trazodone Impurity 33

CAT No: CL-TRZ-33 CAS No: 5520-28-5 Mol Wt: 252.6 Mol F: C10H12Cl3N Inv Status: Custom Synthesis

Chemical Name: 3-Chloro-N,N-bis(2-chloroethyl)aniline

Trazodone Impurity 34

CAT No: CL-TRZ-34 CAS No: 1019115-81-1 Mol Wt: 192.2 Mol F: C9H12N4O Inv Status: Custom Synthesis

Chemical Name: 2-(3-Aminopropyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Trazodone Impurity 35

CAT No: CL-TRZ-35 CAS No: 19666-40-1 Mol Wt: 211.6 Mol F: C9H10ClN3O Inv Status: In Stock

Chemical Name: 2-(3-Chloropropyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Trazodone Impurity 36

CAT No: CL-TRZ-36 CAS No: 101364-27-6 Mol Wt: 307.6 Mol F: C13H17Cl3N2 Inv Status: In Stock

Chemical Name: 1-(3-Chloropropyl)-4-(3,4-dichlorophenyl)piperazine

Trazodone

CAT No: CL-TRZ-37 CAS No: 19794-93-5 ; 25332-39-2 (HCl salt) Mol Wt: 371.9 Mol F: C19H22ClN5O Inv Status: Custom Synthesis

Chemical Name: 2-[3-[4-(3-Chlorophenyl)piperazin-1-yl]propyl][1,2,4]triazolo[4,3-a]pyridin-3(2H)-one ; 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-, (as per USP)

Trazodone Impurity 7

CAT No: CL-TRZ-38 CAS No: 1094305-62-0 Mol Wt: 256.1 Mol F: C9H10BrN3O Inv Status: In Stock

Chemical Name: 2-(3-Bromopropyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Trazodone Di N Oxide

CAT No: CL-TRZ-39 CAS No: 1346603-99-3 Mol Wt: 403.9 Mol F: C19H22ClN5O3 Inv Status: In Stock

Chemical Name: 1-(3-Chlorophenyl)-4-(3-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl)piperazine 1,4-dioxide

Trazodone Impurity 37

CAT No: CL-TRZ-40 CAS No: 328410-01-1 Mol Wt: 317.65 Mol F: C13H18BrClN2 Inv Status: In Stock

Chemical Name: 1-(3-Bromophenyl)-4-(3-chloropropyl)piperazine

Trazodone Impurity 18

CAT No: CL-TRZ-41 CAS No: NA Mol Wt: 238.76 Mol F: C13H19ClN2 Inv Status: In Stock

Chemical Name: 1-(3-chloropropyl)-4-phenylpiperazine

Trazodone Impurity E (HCl salt)

CAT No: CL-TRZ-42 CAS No: NA Mol Wt: 273.2 : 36.5 Mol F: C13H18Cl2N2 : HCl Inv Status: In Stock

Chemical Name: 1-(4-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride

Type:Impurity Reference Standard

Total Products: 41

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