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Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Tapinarof and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Tapinarof impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Tapinarof-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

Tapinarof D5
CAT No: CL-TNOF-01 CAS No: 2748997-80-8 Mol Wt: 259.4 Mol F: C17H13D5O2 Inv Status: Custom Synthesis
Chemical Name: ?2-Isopropyl-5-(styryl)benzene-1,3-diol
(Z)-Dimethoxy Tapinarof
CAT No: CL-TNOF-02 CAS No: 1622988-16-2 Mol Wt: 254.3 Mol F: C19H22O2 Inv Status: Custom Synthesis
Chemical Name: (Z)-2-Isopropyl-1,3-dimethoxy-5-styrylbenzene
4-Methyl Tapinarof
CAT No: CL-TNOF-03 CAS No: 2657659-60-2 Mol Wt: 268.4 Mol F: C18H20O2 Inv Status: Custom Synthesis
Chemical Name: (E)-2-Isopropyl-4-methyl-5-styrylbenzene-1,3-diol
cis-Tapinarof
CAT No: CL-TNOF-04 CAS No: 1622988-14-0 Mol Wt: 254.3 Mol F: C17H18O2 Inv Status: Custom Synthesis
Chemical Name: ?(Z)-2-isopropyl-5-styrylbenzene-1,3-diol
Dimethoxy Tapinarof
CAT No: CL-TNOF-05 CAS No: 141509-20-8 Mol Wt: 282.4 Mol F: C19H22O2 Inv Status: Custom Synthesis
Chemical Name: (E)-2-Isopropyl-1,3-dimethoxy-5-styrylbenzene
Methyl Phenyl Tapinarof
CAT No: CL-TNOF-06 CAS No: 3017211-63-8 Mol Wt: 346.5 Mol F: C24H26O2 Inv Status: Custom Synthesis
Chemical Name: 2-Isopropyl-5-(2-phenyl-2-(p-tolyl)ethyl)benzene-1,3-diol
Tapinarof
CAT No: CL-TNOF-07 CAS No: 79338-84-4 Mol Wt: 254.3 Mol F: C17H18O2 Inv Status: Custom Synthesis
Chemical Name: (E)-2-Isopropyl-5-styrylbenzene-1,3-diol
Tapinarof 1,2-Diyl Dimer Impurity
CAT No: CL-TNOF-08 CAS No: NA Mol Wt: 508.7 Mol F: C34H36O4 Inv Status: Custom Synthesis
Chemical Name: 5,5'-(3,4-Diphenylcyclobutane-1,2-diyl)bis(2-isopropylbenzene-1,3-diol)
Tapinarof 1,3-Diyl Dimer Impurity
CAT No: CL-TNOF-09 CAS No: NA Mol Wt: 508.7 Mol F: C34H36O4 Inv Status: Custom Synthesis
Chemical Name: 5,5'-(2,4-Diphenylcyclobutane-1,3-diyl)bis(2-isopropylbenzene-1,3-diol)
Tapinarof Impurity 10
CAT No: CL-TNOF-10 CAS No: 1627510-05-7 Mol Wt: 210.2 Mol F: C11H14O4 Inv Status: Custom Synthesis
Chemical Name: Methyl 3,5-dihydroxy-4-isopropylbenzoate
Tapinarof Impurity 11
CAT No: CL-TNOF-11 CAS No: 344396-17-4 Mol Wt: 238.3 Mol F: C13H18O4 Inv Status: Custom Synthesis
Chemical Name: Methyl 4-isopropyl-3,5-dimethoxybenzoate
Tapinarof Impurity 2
CAT No: CL-TNOF-12 CAS No: 1265899-59-9 Mol Wt: 254.3 Mol F: C11H15BrO2 Inv Status: Custom Synthesis
Chemical Name: 5-Bromo-2-isopropyl-1,3-dimethoxybenzene
Tapinarof Impurity 3
CAT No: CL-TNOF-13 CAS No: 2772354-76-2 Mol Wt: 266.3 Mol F: C15H22O4 Inv Status: Custom Synthesis
Chemical Name: 2,4-Diisopropyl-3,5-dimethoxybenzoic acid
Tapinarof Impurity 4
CAT No: CL-TNOF-14 CAS No: 1213826-92-6 Mol Wt: 196.2 Mol F: C10H12O4 Inv Status: Custom Synthesis
Chemical Name: 3,5-Dihydroxy-4-isopropylbenzoic acid
Tapinarof Impurity 5
CAT No: CL-TNOF-15 CAS No: 2901016-39-3 Mol Wt: 268.4 Mol F: C18H20O2 Inv Status: Custom Synthesis
Chemical Name: (E)-2-Isopropyl-3-methoxy-5-styrylphenol
Tapinarof Impurity 7
CAT No: CL-TNOF-16 CAS No: 443982-76-1 Mol Wt: 330.4 Mol F: C16H27O5P Inv Status: Custom Synthesis
Chemical Name: Diethyl (4-isopropyl-3,5-dimethoxybenzyl)phosphonate
Tapinarof Impurity 8
CAT No: CL-TNOF-17 CAS No: 2648495-00-3 Mol Wt: 224.3 Mol F: C12H16O4 Inv Status: Custom Synthesis
Chemical Name: Methyl 4-ethyl-3,5-dimethoxybenzoate
Tapinarof Impurity 9
CAT No: CL-TNOF-18 CAS No: 847992-40-9 Mol Wt: 238.3 Mol F: C13H18O4 Inv Status: Custom Synthesis
Chemical Name: Methyl 3,5-dimethoxy-4-propylbenzoate
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