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Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Pyrimethamine and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Pyrimethamine impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Pyrimethamine-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

Pyrimethamine
CAT No: CL-PMHM-01 CAS No: 58-14-0 Mol Wt: 248.7 Mol F: C12H13ClN4 Inv Status: Custom Synthesis
Chemical Name: 5-(4-Chlorophenyl)-6-ethylpyrimidine-2,4-diamine
Pyrimethamine EP Impurity A
CAT No: CL-PMHM-02 CAS No: 55474-40-3 Mol Wt: 207.7 Mol F: C11H10ClNO Inv Status: Custom Synthesis
Chemical Name: (2?)-2-(4-chlorophenyl)-3-oxopentanenitrile
Pyrimethamine EP Impurity B
CAT No: CL-PMHM-03 CAS No: 3275-44-3 Mol Wt: 234.7 Mol F: C11H11ClN4 Inv Status: Custom Synthesis
Chemical Name: 5-(4-chlorophenyl)-6-methylpyrimidine-2,4-diamine
Pyrimethamine EP Impurity D
CAT No: CL-PMHM-04 CAS No: 55474-41-4 Mol Wt: 251.7 Mol F: C13H14ClNO2 Inv Status: Custom Synthesis
Chemical Name: (?)-(4-chlorophenyl)(2-ethyl-1,3-dioxolan-2-yl)acetonitrile
Pyrimethamine BP Impurity 1
CAT No: CL-PMHM-05 CAS No: 91396-20-2 Mol Wt: 249.7 Mol F: C12H12ClN3O Inv Status: Custom Synthesis
Chemical Name: 2-amino-5-(4-chlorophenyl)-6-ethyl-1,4-dihydropyrimidin-4-one
Pyrimethamine BP Impurity 2
CAT No: CL-PMHM-06 CAS No: (5219-07-8) Mol Wt: 193.6 Mol F: C10H8ClNO Inv Status: Custom Synthesis
Chemical Name: 2-(4-chlorophenyl)-3-oxobutanenitrile
Pyrimethamine BP Impurity 3
CAT No: CL-PMHM-07 CAS No: 93456-61-2 Mol Wt: 249.7 Mol F: C12H12ClN3O Inv Status: Custom Synthesis
Chemical Name: 4-amino-5-(4-chlorophenyl)-6-ethyl-1,2-dihydropyrimidin-2-one
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