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Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Nirogacestat and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Nirogacestat impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Nirogacestat-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

Nirogacestat
CAT No: CL-NRG-01 CAS No: 1290543-63-3 Mol Wt: 489.7 Mol F: C27H41F2N5O Inv Status: Custom Synthesis
Chemical Name: (S)-2-(((S)-6,8-Difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide
Racemic Nirogacestat
CAT No: CL-NRG-02 CAS No: 2700683-77-6 Mol Wt: 489.7 Mol F: C27H41F2N5O Inv Status: Custom Synthesis
Chemical Name: 2-((6,8-Difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide
Nirogacestat Impurity 1
CAT No: CL-NRG-03 CAS No: 2869169-69-5 Mol Wt: 506.1 Mol F: C27H41ClFN5O Inv Status: Custom Synthesis
Chemical Name: (S)-2-(((S)-6-Chloro-8-fluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide
Nirogacestat Impurity 2
CAT No: CL-NRG-04 CAS No: 2869169-68-4 Mol Wt: 299.8 Mol F: C15H19ClFNO2 Inv Status: Custom Synthesis
Chemical Name: (S)-2-(((S)-6-Chloro-8-fluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)pentanoic acid
Nirogacestat Impurity 3
CAT No: CL-NRG-05 CAS No: 865774-26-1 Mol Wt: 224.4 Mol F: C12H24N4 Inv Status: Custom Synthesis
Chemical Name: 1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-amine
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