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Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Midazolam and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Midazolam impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Midazolam-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

Midazolam EP Impurity A

CAT No: CL-MDZ-02 CAS No: 59468-07-4 Mol Wt: 327.8 Mol F: C18H15ClFN3 Inv Status: In Stock

Chemical Name: (6RS)-8-chloro-6-(2-fluorophenyl)-1-methyl-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine

Midazolam EP Impurity B

CAT No: CL-MDZ-03 CAS No: 59469-74-8 Mol Wt: 325.8 Mol F: C18H13ClFN3 Inv Status: Custom Synthesis

Chemical Name: (6RS)-8-chloro-6-(2-fluorophenyl)-1-methyl-6H-imidazo[1,5-a][1,4]benzodiazepine

Midazolam EP Impurity E

CAT No: CL-MDZ-04 CAS No: 59467-64-0 Mol Wt: 303.8 Mol F: C16H15ClFN3 Inv Status: Custom Synthesis

Chemical Name: [(2RS)-7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-yl]methanamine

Midazolam EP Impurity G

CAT No: CL-MDZ-05 CAS No: 59467-86-6 Mol Wt: 307.8 Mol F: C18H14ClN3 Inv Status: Custom Synthesis

Chemical Name: 8-Chloro-1-methyl-6-phenyl-4H-imidazo[1,5-a][1,4]benzodiazepine

Midazolam EP Impurity H

CAT No: CL-MDZ-06 CAS No: 119401-13-7 Mol Wt: 272.7 Mol F: C15H10ClFN2 Inv Status: In Stock

Chemical Name: 6-chloro-4-(2-fluorophenyl)-2-methylquinazoline

Midazolam EP Impurity C

CAT No: CL-MDZ-07 CAS No: 59468-44-9 Mol Wt: 369.8 Mol F: C19H13ClFN3O2 Inv Status: Custom Synthesis

Chemical Name: 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid,

Midazolam EP Impurity D

CAT No: CL-MDZ-08 CAS No: 59468-83-6 Mol Wt: 341.8 Mol F: C18H13ClFN3O Inv Status: Custom Synthesis

Chemical Name: 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine 5-oxide,

Midazolam EP Impurity F

CAT No: CL-MDZ-09 CAS No: 2886-65-9 Mol Wt: 288.7 Mol F: C15H10ClFN2O Inv Status: In Stock

Chemical Name: 7-Chloro-5-(2-fluoropheny)-1,3-dihydro-2H-1,4-benzodiazepin-2-one

Midazolam EP Impurity I

CAT No: CL-MDZ-10 CAS No: 59467-69-5 Mol Wt: 327.8 Mol F: C18H15ClFN3 Inv Status: Custom Synthesis

Chemical Name: (3aRS)-8-chloro-6-(2-fluorophenyl)-1-methyl-3a,4-dihydro-3H-imidazo[1,5-a][1,4]benzodiazepine,

Midazolam EP Impurity J

CAT No: CL-MDZ-11 CAS No: 59469-08-8 Mol Wt: 329.8 Mol F: C18H17ClFN3 Inv Status: Custom Synthesis

Chemical Name: 8-Chloro-6-(2-fluorophenyl)-1-methyl-3a,4,5,6-tetrahydro-3H-imidazo[1,5-a][1,4]benzodiazepine.

Midazolam Impurity 1

CAT No: CL-MDZ-13 CAS No: 151921-06-1 Mol Wt: 358.75 Mol F: C18H12ClFN2O3 Inv Status: Custom Synthesis

Chemical Name: 1-(4-Chloro-2-(2-fluorobenzoyl)phenyl)-2-methyl-1H-imidazole-5-carboxylic Acid

Midazolam Impurity 2

CAT No: CL-MDZ-17 CAS No: NA Mol Wt: 357.77 Mol F: C18H13ClFN3O2 Inv Status: Custom Synthesis

Chemical Name: 8-Chloro-6-(2-fluorophenyl)-3a-hydroxy-1-methyl-3a,4-dihydro-3H-benzo[f]imidazo[1,5-a][1,4]diazepin-3-one

Midazolam Impurity 3

CAT No: CL-MDZ-18 CAS No: 84425-62-7 Mol Wt: 343.8 Mol F: C18H15ClFN3O Inv Status: Custom Synthesis

Chemical Name: (2-(5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl)-5-chlorophenyl)(2-fluorophenyl)methanone

1'-Hydroxy Midazolam-d5

CAT No: CL-MDZ-19 CAS No: 1276651-09-2 Mol Wt: 346.8 Mol F: C18H8D5ClFN3O Inv Status: Custom Synthesis

Chemical Name: (8-Chloro-6-(2-fluorophenyl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-1-yl-3,4,4-d3)methan -d2-ol

Midazolam D6

CAT No: CL-MDZ-20 CAS No: 1246819-79-3 Mol Wt: 331.8 Mol F: C18H7D6ClFN3 Inv Status: Custom Synthesis

Chemical Name: 8-Chloro-6-(2-fluorophenyl)-1-(methyl-d3)-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3,4,4- d3

1H-Imidazole-5-Carboxylic Acid

CAT No: CL-MDZ-21 CAS No: 151921-06-1 Mol Wt: 358.8 Mol F: C18H12ClFN2O3 Inv Status: Custom Synthesis

Chemical Name: 1-(4-Chloro-2-(2-fluorobenzoyl)phenyl)-2-methyl-1H-imidazole-5-carboxylic acid

Midazolam Glycol Ether

CAT No: CL-MDZ-22 CAS No: NA Mol Wt: 411.9 Mol F: C22H22ClN3O3 Inv Status: Custom Synthesis

Chemical Name: 2-(2-(2-(8-Chloro-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-6-yl)phenoxy)ethoxy)ethan-1-ol

Midazolam Impurity 11

CAT No: CL-MDZ-23 CAS No: 41282-11-5 Mol Wt: 307.8 Mol F: C18H14ClN3 Inv Status: Custom Synthesis

Chemical Name: 8-Chloro-1-methyl-6-phenyl-4H-benzo[f]imidazo[1,2-a][1,4]diazepine

Midazolam Impurity 7

CAT No: CL-MDZ-24 CAS No: NA Mol Wt: 357.8 Mol F: C18H13ClFN3O2 Inv Status: Custom Synthesis

Chemical Name: 1-(4-Chloro-2-(2-fluorobenzoyl)phenyl)-2-methyl-1H-imidazole-5-carboxamide

1',4-Dihydroxy Midazolam

CAT No: CL-MDZ-25 CAS No: 64740-68-7 Mol Wt: 357.8 Mol F: C18H13ClFN3O2 Inv Status: Custom Synthesis

Chemical Name: 8-Chloro-6-(2-fluorophenyl)-1-(hydroxymethyl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-4-ol

1'-Hydroxy Midazolam

CAT No: CL-MDZ-26 CAS No: 59468-90-5 Mol Wt: 341.8 Mol F: C18H13ClFN3O Inv Status: Custom Synthesis

Chemical Name: (8-Chloro-6-(2-fluorophenyl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-1-yl)methanol

1'-Hydroxy Midazolam-b-D-Glucuronide

CAT No: CL-MDZ-27 CAS No: 81256-81-7 Mol Wt: 517.9 Mol F: C24H21ClFN3O7 Inv Status: Custom Synthesis

Chemical Name: (2S,3S,4S,5R,6R)-6-((8-Chloro-6-(2-fluorophenyl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-1-yl)methoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

4-Acetoxy Midazolam

CAT No: CL-MDZ-28 CAS No: 59468-84-7 Mol Wt: 383.8 Mol F: C20H15ClFN3O2 Inv Status: Custom Synthesis

Chemical Name: 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-4-yl acetate

4-Hydroxy Midazolam

CAT No: CL-MDZ-29 CAS No: 59468-85-8 Mol Wt: 341.8 Mol F: C18H13ClFN3O Inv Status: Custom Synthesis

Chemical Name: 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-4-ol

Midazolam Impurity 4

CAT No: CL-MDZ-30 CAS No: 2454678-38-5 Mol Wt: 342.8 Mol F: C18H12ClFN2O2 Inv Status: Custom Synthesis

Chemical Name: 1-(4-Chloro-2-(2-fluorobenzoyl)phenyl)-2-methyl-1H-imidazole-5-carbaldehyde

Midazolam Impurity 5

CAT No: CL-MDZ-31 CAS No: 59467-63-9 Mol Wt: 331.7 Mol F: C16H11ClFN3O2 Inv Status: Custom Synthesis

Chemical Name: 7-Chloro-5-(2-fluorophenyl)-2-(nitromethylene)-2,3-dihydro-1H-benzo[e][1,4]diazepine

Midazolam Impurity 6

CAT No: CL-MDZ-32 CAS No: 154754-57-1 Mol Wt: 323.8 Mol F: C18H14ClN3O Inv Status: Custom Synthesis

Chemical Name: 6-(8-Chloro-1-methyl-4,5-dihydro-6H-benzo[f]imidazo[1,5-a][1,4]diazepin-6-ylidene)cyclohexa-2,4-dien-1-one

Midazolam Maleic Acid Adduct

CAT No: CL-MDZ-33 CAS No: 2531288-23-8 Mol Wt: 441.8 Mol F: C22H17ClFN3O4 Inv Status: Custom Synthesis

Chemical Name: 3-Carboxy-2-(8-chloro-6-(2-fluorophenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-2-ium-2-yl)propanoate

Midazolam N-Glucuronide

CAT No: CL-MDZ-34 CAS No: 1033824-50-8 Mol Wt: 501.9 Mol F: C24H21ClFN3O6 Inv Status: Custom Synthesis

Chemical Name: (2S,3S,4S,5R,6R)-6-(8-chloro-6-(2-fluorophenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-2-ium-2-yl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate

Midazolam Impurity 10

CAT No: CL-MDZ-35 CAS No: 1645-32-5 Mol Wt: 304.8 Mol F: C15H10ClFN2S Inv Status: Custom Synthesis

Chemical Name: 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-benzo[e][1,4]diazepine-2-thione

Midazolam Impurity 12

CAT No: CL-MDZ-36 CAS No: 60656-72-6 Mol Wt: 325.2 Mol F: C15H11Cl2FN2O Inv Status: Custom Synthesis

Chemical Name: 6-chloro-2-(chloromethyl)-4-(2-fluorophenyl)-1,2-dihydroquinazoline 3-oxide

Midazolam Impurity 13

CAT No: CL-MDZ-37 CAS No: 60656-74-8 Mol Wt: 323.1 Mol F: C15H9Cl2FN2O Inv Status: Custom Synthesis

Chemical Name: 6-chloro-2-(chloromethyl)-4-(2-fluorophenyl)quinazoline 3-oxide

Midazolam Impurity 14

CAT No: CL-MDZ-38 CAS No: 59467-68-4 Mol Wt: 345.8 Mol F: C18H17ClFN3O Inv Status: Custom Synthesis

Chemical Name: N-((7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methyl)acetamide

Midazolam Impurity 8

CAT No: CL-MDZ-39 CAS No: 59469-07-7 Mol Wt: 305.8 Mol F: C16H17ClFN3 Inv Status: Custom Synthesis

Chemical Name: (7-chloro-5-(2-fluorophenyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine

Midazolam Impurity 9

CAT No: CL-MDZ-40 CAS No: 59467-61-7 Mol Wt: 301.7 Mol F: C16H13ClFN3 Inv Status: Custom Synthesis

Chemical Name: 7-Chloro-5-(2-fluorophenyl)-N-methyl-3H-benzo[e][1,4]diazepin-2-amine

1'-Hydroxy Midazolam-13C3

CAT No: CL-MDZ-41 CAS No: 1189677-14-2 Mol Wt: 344.7 Mol F: C1513C3H13ClFN3O Inv Status: Custom Synthesis

Chemical Name: (8-chloro-6-(2-fluorophenyl)-4H-benzo[f]imidazo[3,4-a][1,4]diazepin-1-yl-1,3a-13C2)methanol-13C

Midazolam D5

CAT No: CL-MDZ-42 CAS No: 395067-42-2 Mol Wt: 330.8 Mol F: C18H8D5ClFN3 Inv Status: Custom Synthesis

Chemical Name: 8-Chloro-6-(2-fluorophenyl-3,5-d2)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3,4,4-d3

Midazolam D3

CAT No: CL-MDZ-43 CAS No: NA Mol Wt: 328.8 Mol F: C18H10D3ClFN3 Inv Status: Custom Synthesis

Chemical Name: 8-Chloro-6-(2-fluorophenyl)-1-(methyl-d3)-4H-benzo[f]imidazo[1,5-a][1,4]diazepine

Type:Impurity Reference Standard

Total Products: 38

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