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Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Hydroxychloroquine and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Hydroxychloroquine impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Hydroxychloroquine-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

Hydroxychloroquine Sulfate

CAT No: CL-HCQ-01 CAS No: 747-36-4 Mol Wt: 335.9 : 98.1 Mol F: C18H26ClN3O: H2SO4 Inv Status: Custom Synthesis

Chemical Name: 2-[[(4RS)-4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethan-1-ol sulfate ; (?-2-[[4-[(7-Chloro-4-quinolyl)amino]pentyl]ethylamino]ethanol sulfate (1:1) (salt) (as per USP)

Desethyl Hydroxy Chloroquine HCl

CAT No: CL-HCQ-02 CAS No: NA Mol Wt: 307.8 Mol F: C16H22ClN3O Inv Status: Custom Synthesis

Chemical Name: 2-amino-6-((7-Chloroquinolin-4-yl)amino)heptan-1-ol

Hydroxychloroquine Impurity 20

CAT No: CL-HCQ-03 CAS No: 47493-14-1 Mol Wt: 377.9 Mol F: C20H28ClN3O2 Inv Status: In Stock

Chemical Name: 2-({4-[(7-Chloroquinolin-4-yl)amino]pentyl}ethylamino)ethyl acetate

Hydroxychloroquine EP Impurity F

CAT No: CL-HCQ-04 CAS No: 6281-58-9 Mol Wt: 246.7 Mol F: C14H15ClN2 Inv Status: Custom Synthesis

Chemical Name: 7-Chloro-4-[(2RS)-2-methylpyrrolidin-1-yl]quinoline

Hydroxychloroquine R-Isomer Impurity

CAT No: CL-HCQ-05 CAS No: 137433-23-9 Mol Wt: 335.9 Mol F: C18H26ClN3O Inv Status: Custom Synthesis

Chemical Name: (R)-2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethan-1-ol

Hydroxychloroquine S-Isomer Impurity

CAT No: CL-HCQ-06 CAS No: 137433-24-0 Mol Wt: 335.9 Mol F: C18H26ClN3O Inv Status: Custom Synthesis

Chemical Name: (S)-2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethan-1-ol

Hydroxychloroquine O-Acetate

CAT No: CL-HCQ-07 CAS No: NA Mol Wt: 349.9 Mol F: C18H24ClN3O2 Inv Status: Custom Synthesis

Chemical Name: 2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)amino)ethyl acetate

Hydroxychloroquine O-Sulfate

CAT No: CL-HCQ-08 CAS No: NA Mol Wt: 437.9 Mol F: C18H25ClN3NaO4S Inv Status: Custom Synthesis

Chemical Name: Sodium 2-((4-((7-chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethyl sulfate

Hydroxychloroquine Impurity I

CAT No: CL-HCQ-09 CAS No: NA Mol Wt: 469.4 Mol F: C25H26Cl2N4O Inv Status: Custom Synthesis

Chemical Name: 2-((4-((6-Chloronaphthalen-1-yl)amino)pentyl)(7-chloroquinolin-4-yl)amino)ethan-1-ol

Hydroxychloroquine EP Impurity A (N-Oxide)

CAT No: CL-HCQ-10 CAS No: 1449223-88-4 Mol Wt: 351.87 Mol F: C18H26ClN3O2 Inv Status: In Stock

Chemical Name: 4-[(7-chloroquinolin-4-yl)amino]-N-ethyl-N-(hydroxyethyl)pentan-1-amine N-oxide

Hydroxychloroquine Impurity E (Dimer)

CAT No: CL-HCQ-11 CAS No: NA Mol Wt: 653.7 : 2(36.5) Mol F: C36H50Cl2N6O : 2(HCl) Inv Status: Custom Synthesis

Chemical Name: 2-((4-((7-Chloroquinolin-4-yl)(2-((4-((7-chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethyl)amino)pentyl)(ethyl)amino)ethan-1-ol dihydrochloride

Hydroxychloroquine Impurity 1

CAT No: CL-HCQ-12 CAS No: 2518282-96-5 Mol Wt: 453.4 Mol F: C25H26Cl2N4 Inv Status: Custom Synthesis

Chemical Name: N1,N4-Bis(7-chloroquinolin-4-yl)-N1-ethylpentane-1,4-diamine

Hydroxychloroquine Impurity 2

CAT No: CL-HCQ-13 CAS No: NA Mol Wt: 335.9 Mol F: C18H26ClN3O Inv Status: Custom Synthesis

Chemical Name: 2-((4-((5-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethan-1-ol

Hydroxychloroquine Impurity 3

CAT No: CL-HCQ-14 CAS No: 2411340-31-1 Mol Wt: 335.9 Mol F: C18H26ClN3O Inv Status: Custom Synthesis

Chemical Name: N1-(2-((7-Chloroquinolin-4-yl)oxy)ethyl)-N1-ethylpentane-1,4-diamine

De-Ethyl Chloroquine (Impurity D)

CAT No: CL-HCQ-15 CAS No: 1476-52-4 Mol Wt: 291.8 Mol F: C16H22ClN3 Inv Status: Custom Synthesis

Chemical Name: (4RS)-N4-(7-chloroquinolin-4-yl)-N1-ethylpentane-1,4-diamine Hydrochloride

Hydroxychloroquine Impurity 4

CAT No: CL-HCQ-16 CAS No: 21617-12-9 Mol Wt: 198 Mol F: C9H5Cl2N Inv Status: Custom Synthesis

Chemical Name: 4,8-Dichloroquinoline

Hydroxychloroquine EP Impurity G

CAT No: CL-HCQ-17 CAS No: 86-98-6 Mol Wt: 198.05 Mol F: C9H5Cl2N Inv Status: In Stock

Chemical Name: 4,7-Dichloroquinoline

4,5-Dichloroquinoline

CAT No: CL-HCQ-18 CAS No: 21617-18-5 Mol Wt: 198 Mol F: C9H5Cl2N Inv Status: Custom Synthesis

Chemical Name: 4,5-Dichloroquinoline

Hydroxychloroquine

CAT No: CL-HCQ-19 CAS No: 118-42-3 Mol Wt: 335.9 Mol F: C18H26ClN3O Inv Status: Custom Synthesis

Chemical Name: 2-[[(4RS)-4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethan-1-ol (as per EP); (?)-2-[[4-[(7-Chloro-4-quinolyl)amino]pentyl]ethylamino]ethanol (as per USP)

Hydroxychloroquine EP Impurity C (2HCl salt)

CAT No: CL-HCQ-20 CAS No: 2732277-18-6 Mol Wt: 307.8 : 2(36.5) Mol F: C16H22ClN3O : 2(HCl) Inv Status: Custom Synthesis

Chemical Name: 2-[[(4RS)-4-[(7-chloroquinolin-4-yl)amino]pentyl]amino]ethan-1-ol Dihydrochloride (as per EP)2-({4-[(7-Chloroquinolin-4-yl)amino]pentyl}amino)ethan-1-ol Dihydrochloride (as per USP)

Hydroxychloroquine EP Impurity D Hydrochloride

CAT No: CL-HCQ-21 CAS No: [4298-11-7] Mol Wt: 291.8 : 36.5 Mol F: C16H22ClN3 : HCl Inv Status: Custom Synthesis

Chemical Name: (4RS)-N4-(7-chloroquinolin-4-yl)-N1-ethylpentane-1,4-diamine Hydrochloride (as per EP)

Hydroxychloroquine EP Impurity E

CAT No: CL-HCQ-22 CAS No: 10500-64-8 Mol Wt: 264.8 Mol F: C14H17ClN2O Inv Status: Custom Synthesis

Chemical Name: (4RS)-4-[(7-Chloroquinolin-4-yl)amino]pentan-1-ol (as per EP)

Hydroxychloroquine Impurity 7

CAT No: CL-HCQ-23 CAS No: 927-55-9 Mol Wt: 103.2 Mol F: C5H13NO Inv Status: Custom Synthesis

Chemical Name: 4-Aminopentan-1-ol

Hydroxychloroquine Impurity 9

CAT No: CL-HCQ-24 CAS No: 86-47-5 Mol Wt: 223.6 Mol F: C10H6ClNO3 Inv Status: Custom Synthesis

Chemical Name: 7-Chloro-4-hydroxyquinoline-3-carboxylic acid

Hydroxychloroquine Sulfate EP Impurity B

CAT No: CL-HCQ-25 CAS No: 103152-84-7 Mol Wt: 415.9 Mol F: C18H26ClN3O4S Inv Status: Custom Synthesis

Chemical Name: 2-[[(4RS)-4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethyl hydrogen sulfate (as per EP); 2-({4-[(7-Chloroquinolin-4-yl)amino]pentyl}ethylamino)ethyl hydrogen sulfate (as per USP)

3,7-Dichloro Hydroxychloroquine

CAT No: CL-HCQ-26 CAS No: 2054858-86-3 Mol Wt: 370.3 Mol F: C18H25Cl2N3O Inv Status: Custom Synthesis

Chemical Name: 2-((4-((3,7-Dichloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethanol

3-Cyclopropyl Hydroxychloroquine

CAT No: CL-HCQ-27 CAS No: 2054859-10-6 Mol Wt: 375.9 Mol F: C21H30ClN3O Inv Status: Custom Synthesis

Chemical Name: 2-((4-((7-Chloro-3-cyclopropylquinolin-4-yl)amino)pentyl)(ethyl)amino)ethanol

3-Trifluoromethyl Hydroxychloroquine

CAT No: CL-HCQ-28 CAS No: 2054858-88-5 Mol Wt: 403.9 Mol F: C19H25ClF3N3O Inv Status: Custom Synthesis

Chemical Name: 2-((4-((7-Chloro-3-(trifluoromethyl)quinolin-4-yl)amino)pentyl)(ethyl)amino)ethanol

4-Amino-1-(diethylamino)pentane

CAT No: CL-HCQ-29 CAS No: 140-80-7 Mol Wt: 158.3 Mol F: C9H22N2 Inv Status: Custom Synthesis

Chemical Name: N1,N1-Diethylpentane-1,4-diamine

5,7-Dichloro Hydroxychloroquine

CAT No: CL-HCQ-30 CAS No: 2054858-98-7 Mol Wt: 370.3 Mol F: C18H25Cl2N3O Inv Status: Custom Synthesis

Chemical Name: 2-((4-((5,7-Dichloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethanol

6,7-Dichloro Hydroxychloroquine

CAT No: CL-HCQ-31 CAS No: 2054859-04-8 Mol Wt: 370.3 Mol F: C18H25Cl2N3O Inv Status: Custom Synthesis

Chemical Name: 2-((4-((6,7-Dichloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethanol

7-Chloro-3-iodo Hydroxychloroquine

CAT No: CL-HCQ-32 CAS No: 161618-30-0 Mol Wt: 461.8 Mol F: C18H25ClIN3O Inv Status: Custom Synthesis

Chemical Name: 2-((4-((7-Chloro-3-iodoquinolin-4-yl)amino)pentyl)(ethyl)amino)ethan-1-ol

7-Fluoro Hydroxychloroquine

CAT No: CL-HCQ-33 CAS No: 478784-65-5 Mol Wt: 319.4 Mol F: C18H26FN3O Inv Status: Custom Synthesis

Chemical Name: 2-[Ethyl[4-[(7-fluoro-4-quinolinyl)amino]pentyl]amino]ethanol

Desethyl hydrochloroquine-O-Acetate

CAT No: CL-HCQ-34 CAS No: NA Mol Wt: 349.9 Mol F: C18H24ClN3O2 Inv Status: Custom Synthesis

Chemical Name: 2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)amino)ethyl acetate

Hydroxychloroquine 3-Bromo Impurity

CAT No: CL-HCQ-35 CAS No: 2054859-08-2 Mol Wt: 414.8 Mol F: C18H25BrClN3O Inv Status: Custom Synthesis

Chemical Name: 2-((4-((3-Bromo-7-chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethan-1-ol

Hydroxychloroquine 3-Carbonitrile

CAT No: CL-HCQ-36 CAS No: 2054858-84-1 Mol Wt: 360.9 Mol F: C19H25ClN4O Inv Status: Custom Synthesis

Chemical Name: 7-Chloro-4-[[4-[ethyl(2-hydroxyethyl)amino]-1-methylbutyl]amino]-3-Quinolinecarbonitrile

Hydroxychloroquine Acid

CAT No: CL-HCQ-37 CAS No: 645406-24-2 Mol Wt: 365.9 Mol F: C18H24ClN3O3 Inv Status: Custom Synthesis

Chemical Name: 2-((7-Chloroquinolin-4-yl)amino)-5-(ethyl(2-hydroxyethyl)amino)pentanoic acid

Hydroxychloroquine Diethanol

CAT No: CL-HCQ-38 CAS No: 103396-22-1 Mol Wt: 365.9 Mol F: C19H28ClN3O2 Inv Status: Custom Synthesis

Chemical Name: 2,2'-((4-((7-Chloro-3-methylquinolin-4-yl)amino)pentyl)azanediyl)diethanol

Hydroxychloroquine Impurity 10

CAT No: CL-HCQ-39 CAS No: 860544-46-3 Mol Wt: 130.2 Mol F: C7H18N2 Inv Status: Custom Synthesis

Chemical Name: N1-Ethylpentane-1,4-diamine

Hydroxychloroquine Impurity 11

CAT No: CL-HCQ-40 CAS No: 630067-21-9 Mol Wt: 242.1 Mol F: C10H5Cl2NO2 Inv Status: Custom Synthesis

Chemical Name: 4,7-Dichloroquinoline-3-carboxylic acid

Hydroxychloroquine Impurity 12

CAT No: CL-HCQ-41 CAS No: NA Mol Wt: 497.5 Mol F: C27H30Cl2N4O Inv Status: Custom Synthesis

Chemical Name: 2-((4-(Bis(7-chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethan-1-ol

Hydroxychloroquine Impurity 13

CAT No: CL-HCQ-42 CAS No: 2411340-32-2 Mol Wt: 497.5 Mol F: C27H30Cl2N4O Inv Status: Custom Synthesis

Chemical Name: N4-(7-Chloroquinolin-4-yl)-N1-(2-((7-chloroquinolin-4-yl)oxy)ethyl)-N1-ethylpentane-1,4-diamine

Hydroxychloroquine Impurity 14

CAT No: CL-HCQ-43 CAS No: NA Mol Wt: 307.8 Mol F: C16H22ClN3O Inv Status: Custom Synthesis

Chemical Name: 7-Chloro-4-((5-(ethylamino)pentan-2-yl)amino)quinolin-2(1H)-one

Hydroxychloroquine Impurity 15

CAT No: CL-HCQ-44 CAS No: 91911-59-0 Mol Wt: 250.7 Mol F: C13H15ClN2O Inv Status: Custom Synthesis

Chemical Name: 2-((7-Chloroquinolin-4-yl)(ethyl)amino)ethan-1-ol

Hydroxychloroquine Impurity 16

CAT No: CL-HCQ-45 CAS No: NA Mol Wt: 407.9 Mol F: C20H26ClN3O4 Inv Status: Custom Synthesis

Chemical Name: 2-((2-((7-Chloro-2-oxo-1,2-dihydroquinolin-4-yl)amino)heptan-2-yl)amino)-2-oxoethyl acetate

Hydroxychloroquine Impurity 18

CAT No: CL-HCQ-46 CAS No: NA Mol Wt: 308.8 Mol F: C16H21ClN2O2 Inv Status: Custom Synthesis

Chemical Name: 2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)oxy)ethan-1-ol

Hydroxychloroquine Impurity 19

CAT No: CL-HCQ-47 CAS No: 5428-61-5 Mol Wt: 319.9 Mol F: C18H26ClN3 Inv Status: Custom Synthesis

Chemical Name: N4-(5-Chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine

Hydroxychloroquine Impurity 21

CAT No: CL-HCQ-48 CAS No: 84979-83-9 Mol Wt: 175.3 Mol F: C9H21NO2 Inv Status: Custom Synthesis

Chemical Name: 5-(Ethyl(2-hydroxyethyl)amino)pentan-2-ol

Hydroxychloroquine Impurity 5

CAT No: CL-HCQ-49 CAS No: 159346-86-8 Mol Wt: 174.3 Mol F: C9H22N2O Inv Status: Custom Synthesis

Chemical Name: (R)-2-((4-Aminopentyl)(ethyl)amino)ethan-1-ol

Hydroxychloroquine Impurity 6

CAT No: CL-HCQ-50 CAS No: NA Mol Wt: 335.9 Mol F: C18H26ClN3O Inv Status: Custom Synthesis

Chemical Name: (R)-2-((4-((6-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethan-1-ol

N-(Glycoloyloxy)-succinimide

CAT No: CL-HCQ-52 CAS No: 19374-87-9 Mol Wt: 173.1 Mol F: C6H7NO5 Inv Status: Custom Synthesis

Chemical Name: 2-Hydroxy-acetic Acid 2,5-Dioxo-1-pyrrolidinyl Ester

N-Chloromethyl Hydroxychloroquine

CAT No: CL-HCQ-53 CAS No: 1159208-89-5 Mol Wt: 385.4 Mol F: C19H28Cl2N3O Inv Status: Custom Synthesis

Chemical Name: N-(Chloromethyl)-4-((7-chloroquinolin-4-yl)amino)-N-ethyl-N-(2-hydroxyethyl)pentan-1-aminium

N-Propiononitrile Hydroxychloroquine

CAT No: CL-HCQ-54 CAS No: 1606176-76-4 Mol Wt: 388.9 Mol F: C21H29ClN4O Inv Status: Custom Synthesis

Chemical Name: 3-((7-Chloroquinolin-4-yl)(5-(ethyl(2-hydroxyethyl)amino)pentan-2-yl)amino)propanenitrile

Synthetic impurity mixture of HCQS

CAT No: CL-HCQ-55 CAS No: NA Mol Wt: 307.8 : 415.9 Mol F: C16H22ClN3O : C18H26ClN3O4S Inv Status: Custom Synthesis

Chemical Name: 2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)amino)ethan-1-ol 2-((4-((7-chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethyl sulfate

2,5-Dichloroquinoline

CAT No: CL-HCQ-56 CAS No: 59412-12-3 Mol Wt: 198 Mol F: C9H5Cl2N Inv Status: Custom Synthesis

Chemical Name: 2,5-Dichloroquinoline

Bis-Desethyl chlorquine

CAT No: CL-HCQ-57 CAS No: 4298-14-0 Mol Wt: 263.8 Mol F: C14H18ClN3 Inv Status: Custom Synthesis

Chemical Name: N4-(7-Chloroquinolin-4-yl)pentane-1,4-diamine

Type:Impurity Reference Standard

Total Products: 56

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