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Enzalutamide is an androgen receptor inhibitor used in the treatment of metastatic castration-resistant prostate cancer. It works by binding to androgen receptors and inhibiting androgen signaling, which is necessary for the growth of prostate cancer cells.

Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Enzalutamide and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Enzalutamide impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Enzalutamide-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

Desfluro Enzalutamide

CAT No: CL-EZL-01 CAS No: 915087-16-0 Mol Wt: 446.5 Mol F: C21H17F3N4O2S Inv Status: Custom Synthesis

Chemical Name: 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-N-methylbenzamide

Enzalutamide

CAT No: CL-EZL-02 CAS No: 915087-33-1 Mol Wt: 464.4 Mol F: C21H16F4N4O2S Inv Status: Custom Synthesis

Chemical Name: 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide ;

Enzalutamide Impurity C

CAT No: CL-EZL-03 CAS No: 1798807-39-2 Mol Wt: 396.36 Mol F: C17H12F4N4OS Inv Status: In Stock

Chemical Name: 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)thioureido)-2-fluoro-N-methylbenzamide

Enzalutamide Impurity J

CAT No: CL-EZL-04 CAS No: 1895865-11-8 Mol Wt: 398.26 Mol F: C17H8F6N4O Inv Status: In Stock

Chemical Name: 1,3-bis(4-cyano-3-(trifluoromethyl)phenyl)urea

Enzalutamide Impurity 3

CAT No: CL-EZL-05 CAS No: 915087-32-0 Mol Wt: 235.26 Mol F: C12H14FN3O Inv Status: In Stock

Chemical Name: 4-(2-Cyanopropan-2-ylamino)-2-fluoro-N-methylbenzamide

Enzalutamide Impurity 1

CAT No: CL-EZL-06 CAS No: 1258638-92-4 Mol Wt: 282.31 Mol F: C14H19FN2O3 Inv Status: In Stock

Chemical Name: (ethyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate)

Enzalutamide Impurity-2

CAT No: CL-EZL-07 CAS No: 1332524-01-2 Mol Wt: 268.28 Mol F: C13H17FN2O3 Inv Status: In Stock

Chemical Name: methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate

Enzalutamide Impurity-5

CAT No: CL-EZL-08 CAS No: 915087-25-1 Mol Wt: 212.26 Mol F: C11H17FN2O Inv Status: In Stock

Chemical Name: 4-Amino-2-fluro-N-Methylbenzamide

Enzalutamide Impurity P

CAT No: CL-EZL-09 CAS No: 1289942-66-0 Mol Wt: 254.26 Mol F: C12H15FN2O3 Inv Status: In Stock

Chemical Name: 2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid

Enzalutamide Impurity 34

CAT No: CL-EZL-10 CAS No: 654-70-6 Mol Wt: 186.13 Mol F: C8H5F3N2 Inv Status: In Stock

Chemical Name: 4-Amino-2-(trifluoromethyl)benzonitrile

Enzalutamide Impurity A

CAT No: CL-EZL-11 CAS No: 1895865-10-7 Mol Wt: 260.24 Mol F: C10H7F3N2OS Inv Status: In Stock

Chemical Name: O-Methyl (4-Cyano-3-(trifluoromethyl)phenyl)carbamothioate

Enzalutamide Impurity B

CAT No: CL-EZL-12 CAS No: 1839619-50-9 Mol Wt: 414.33 Mol F: C17H8F6N4S Inv Status: In Stock

Chemical Name: 1,3-bis(4-cyano-3-(trifluoromethyl)phenyl)thiourea

Enzalutamide Impurity D

CAT No: CL-EZL-13 CAS No: 1289942-55-7 Mol Wt: 422.4 Mol F: C20H18F4N4O2 Inv Status: In Stock

Chemical Name: 4-((1-((4-Cyano-3-(trifluoromethyl)phenyl)amino)-2-methyl-1-oxopropan-2-yl)amino)-2-fluoro-N-methylbenzamide

Enzalutamide Impurity 42

CAT No: CL-EZL-14 CAS No: NA Mol Wt: 203.1 Mol F: C7H4F3N3O Inv Status: Custom Synthesis

Chemical Name: 5-(Hydroxyamino)-3-(trifluoromethyl)picolinonitrile

Enzalutamide Impurity 11

CAT No: CL-EZL-15 CAS No: NA Mol Wt: 397.4 Mol F: C20H16FN3O3S Inv Status: Custom Synthesis

Chemical Name: 2-Fluoro-4-(3-(4-isocyano-3-methylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)benzoic acid

Enzalutamide Impurity 16

CAT No: CL-EZL-16 CAS No: NA Mol Wt: 244.1 Mol F: C9H10BrNO2 Inv Status: Custom Synthesis

Chemical Name: Methyl 3-amino-2-(bromomethyl)benzoate

Enzalutamide Impurity 19

CAT No: CL-EZL-17 CAS No: NA Mol Wt: 449.4 Mol F: C22H19F4N3O3 Inv Status: Custom Synthesis

Chemical Name: 4-(4-((4-Cyano-3-(trifluoromethyl)phenyl)amino)-3,3-dimethyl-1,4-dioxobutan-2-yl)-2-fluoro-N-methylbenzamide

Enzalutamide Impurity 20

CAT No: CL-EZL-18 CAS No: 1903367-21-4 Mol Wt: 251.3 Mol F: C13H17NO4 Inv Status: Custom Synthesis

Chemical Name: Methyl 4-((1-methoxy-2-methyl-1-oxopropan-2-yl)amino)benzoate

Enzalutamide Impurity 21

CAT No: CL-EZL-19 CAS No: NA Mol Wt: 436.4 Mol F: C20H16F4N4O3 Inv Status: Custom Synthesis

Chemical Name: 4-(N-(1-((4-Cyano-3-(trifluoromethyl)phenyl)amino)-2-methyl-1-oxopropan-2-yl)formamido)-2-fluorobenzamide

Enzalutamide Impurity 22

CAT No: CL-EZL-20 CAS No: 1187368-67-7 Mol Wt: 182.2 Mol F: C9H11FN2O Inv Status: Custom Synthesis

Chemical Name: 4-Amino-2-fluoro-N,N-dimethylbenzamide

Enzalutamide Impurity 24

CAT No: CL-EZL-21 CAS No: NA Mol Wt: 184.2 Mol F: C8H9FN2O2 Inv Status: Custom Synthesis

Chemical Name: 2-Fluoro-4-(hydroxyamino)-N-methylbenzamide

Enzalutamide Impurity 25

CAT No: CL-EZL-22 CAS No: 320-47-8 Mol Wt: 216.1 Mol F: C8H3F3N2O2 Inv Status: Custom Synthesis

Chemical Name: 4-Nitro-2-(trifluoromethyl)benzonitrile

Enzalutamide Impurity 26

CAT No: CL-EZL-23 CAS No: 1705583-65-8 Mol Wt: 247.2 Mol F: C9H4F3NO2S Inv Status: Custom Synthesis

Chemical Name: 4-Isothiocyanato-2-(trifluoromethyl)benzoic acid

Enzalutamide Impurity 27

CAT No: CL-EZL-24 CAS No: NA Mol Wt: 246.2 Mol F: C9H5F3N2OS Inv Status: Custom Synthesis

Chemical Name: 4-Isothiocyanato-2-(trifluoromethyl)benzamide

Enzalutamide Impurity 28

CAT No: CL-EZL-25 CAS No: NA Mol Wt: 412.3 Mol F: C18H10F6N4O Inv Status: Custom Synthesis

Chemical Name: 1,3-Bis(4-cyano-3-(trifluoromethyl)phenyl)-1-methylurea

Enzalutamide Impurity 29

CAT No: CL-EZL-26 CAS No: NA Mol Wt: 601.6 Mol F: C28H20F5N5O3S Inv Status: Custom Synthesis

Chemical Name: 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-(3-fluoro-4-(methylcarbamoyl)phenyl)benzamide

Enzalutamide Impurity 30

CAT No: CL-EZL-28 CAS No: 1895865-08-3 Mol Wt: 349.3 Mol F: C16H10F3N3OS Inv Status: Custom Synthesis

Chemical Name: N-((4-Cyano-3-(trifluoromethyl)phenyl)carbamothioyl)benzamide

Enzalutamide Impurity 33

CAT No: CL-EZL-29 CAS No: NA Mol Wt: 381.3 Mol F: C17H11F4N3OS Inv Status: Custom Synthesis

Chemical Name: 1-(4-Acetyl-3-fluorophenyl)-3-(4-cyano-3-(trifluoromethyl)phenyl)thiourea

Enzalutamide Impurity 35

CAT No: CL-EZL-30 CAS No: 143782-18-7 Mol Wt: 212.1 Mol F: C9H3F3N2O Inv Status: Custom Synthesis

Chemical Name: 4-Isocyanato-2-(trifluoromethyl)benzonitrile

Enzalutamide Impurity 36

CAT No: CL-EZL-31 CAS No: 2341510-75-4 Mol Wt: 276.3 Mol F: C10H7F3N2S2 Inv Status: Custom Synthesis

Chemical Name: Methyl (4-cyano-3-(trifluoromethyl)phenyl)carbamodithioate

Enzalutamide Impurity 37

CAT No: CL-EZL-32 CAS No: 24115-24-0 Mol Wt: 318.9 Mol F: C7H4Br2F3N Inv Status: Custom Synthesis

Chemical Name: 2,4-Dibromo-5-(trifluoromethyl)aniline

Enzalutamide Impurity 39

CAT No: CL-EZL-33 CAS No: NA Mol Wt: 212.1 Mol F: C8H3F3N4 Inv Status: Custom Synthesis

Chemical Name: 5-Amino-3-(trifluoromethyl)pyridine-2,4-dicarbonitrile

Enzalutamide Impurity E

CAT No: CL-EZL-34 CAS No: NA Mol Wt: 619.5 Mol F: C28H16F7N5O2S Inv Status: Custom Synthesis

Chemical Name: N-[4-cyano-3-(trifluoromethyl) phenyl]-4-{3-[4-cyano-3-(trifluoromethyl) phenyl]-5, 5-dimethyl- 4-oxo-2-thioimidazol-1-yl}- 2-fluorobenzamide

Enzalutamide Impurity 40

CAT No: CL-EZL-35 CAS No: NA Mol Wt: 230.2 Mol F: C8H5F3N4O Inv Status: Custom Synthesis

Chemical Name: 5-Amino-2-cyano-3-(trifluoromethyl)isonicotinamide

Enzalutamide Impurity 45

CAT No: CL-EZL-37 CAS No: 1067225-60-8 Mol Wt: 214.1 Mol F: C9H5F3N2O Inv Status: Custom Synthesis

Chemical Name: N-(4-Cyano-3-(trifluoromethyl)phenyl)formamide

Enzalutamide Impurity 46

CAT No: CL-EZL-38 CAS No: NA Mol Wt: 466.4 Mol F: C21H18F4N4O4 Inv Status: Custom Synthesis

Chemical Name: 4-(3-(4-Carbamoyl-3-(trifluoromethyl)phenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide

Enzalutamide Impurity 48

CAT No: CL-EZL-39 CAS No: NA Mol Wt: 239.2 Mol F: C12H14FNO3 Inv Status: Custom Synthesis

Chemical Name: 2-((4-Acetyl-3-fluorophenyl)amino)-2-methylpropanoic acid

Enzalutamide Impurity 49

CAT No: CL-EZL-40 CAS No: NA Mol Wt: 198.2 Mol F: C8H7FN2O3 Inv Status: Custom Synthesis

Chemical Name: 2-(Fluoromethyl)-4-nitrobenzamide

Enzalutamide Impurity 50

CAT No: CL-EZL-41 CAS No: NA Mol Wt: 462.5 Mol F: C21H17F3N4OS2 Inv Status: Custom Synthesis

Chemical Name: 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-2,4-dithioxoimidazolidin-1-yl)-N-methylbenzamide

Enzalutamide Impurity 55

CAT No: CL-EZL-42 CAS No: 350-32-3 Mol Wt: 184.1 Mol F: C7H5FN2O3 Inv Status: Custom Synthesis

Chemical Name: 2-Fluoro-4-nitrobenzamide

Enzalutamide Impurity 56

CAT No: CL-EZL-43 CAS No: 2585-23-1 Mol Wt: 180.2 Mol F: C8H8N2O3 Inv Status: Custom Synthesis

Chemical Name: N-Methyl-4-nitrobenzamide

Enzalutamide Impurity 57

CAT No: CL-EZL-44 CAS No: 1301189-82-1 Mol Wt: 198.2 Mol F: C8H7FN2O3 Inv Status: Custom Synthesis

Chemical Name: 2-Fluoro-N-methyl-3-nitrobenzamide

Enzalutamide Impurity 58

CAT No: CL-EZL-45 CAS No: 136146-83-3 Mol Wt: 198.2 Mol F: C8H7FN2O3 Inv Status: Custom Synthesis

Chemical Name: 2-Fluoro-N-methyl-5-nitrobenzamide

Enzalutamide Impurity 59

CAT No: CL-EZL-46 CAS No: 1257997-37-7 Mol Wt: 198.2 Mol F: C8H7FN2O3 Inv Status: Custom Synthesis

Chemical Name: 2-Fluoro-N-methyl-6-nitrobenzamide

Enzalutamide Impurity 60

CAT No: CL-EZL-47 CAS No: NA Mol Wt: 210.2 Mol F: C10H11FN2O2 Inv Status: Custom Synthesis

Chemical Name: 4-Acetamido-2-fluoro-N-methylbenzamide

Enzalutamide Impurity 61

CAT No: CL-EZL-48 CAS No: NA Mol Wt: 368.4 Mol F: C18H25FN2O5 Inv Status: Custom Synthesis

Chemical Name: 1-Ethoxy-2-methyl-1-oxopropan-2-yl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate

Enzalutamide Impurity 62

CAT No: CL-EZL-49 CAS No: NA Mol Wt: 527.5 Mol F: C26H17F4N3O3S Inv Status: Custom Synthesis

Chemical Name: Phenyl 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluorobenzoate

Enzalutamide Impurity 64

CAT No: CL-EZL-50 CAS No: NA Mol Wt: 208.2 Mol F: C11H13FN2O Inv Status: Custom Synthesis

Chemical Name: 2-Fluoro-N-methyl-4-(propan-2-ylideneamino)benzamide

Enzalutamide Impurity 65

CAT No: CL-EZL-51 CAS No: 52833-63-3 Mol Wt: 153.2 Mol F: C8H8FNO Inv Status: Custom Synthesis

Chemical Name: 2-Fluoro-N-methylbenzamide

Enzalutamide Impurity 66

CAT No: CL-EZL-52 CAS No: 2029195-97-7 Mol Wt: 450.4 Mol F: C21H18F4N4O3 Inv Status: Custom Synthesis

Chemical Name: 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-5,5-dimethyl-4-oxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide

Enzalutamide Impurity F

CAT No: CL-EZL-53 CAS No: 2810090-73-2 Mol Wt: 672.6 Mol F: C30H18F6N6O2S2 Inv Status: Custom Synthesis

Chemical Name: 4-(3-(1-(4-cyano-3-(trifluoromethyl)phenyl)-3-methyl-4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazolin-7-yl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile

Enzalutamide Impurity O

CAT No: CL-EZL-54 CAS No: 1242137-17-2 Mol Wt: 434.4 Mol F: C20H14F4N4O3 Inv Status: Custom Synthesis

Chemical Name: 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-yl)-2-fluorobenzamide

Enzalutamide Impurity 67

CAT No: CL-EZL-55 CAS No: 1802242-47-2 Mol Wt: 269.3 Mol F: C13H16FNO4 Inv Status: Custom Synthesis

Chemical Name: Methyl 2-fluoro-4-((1-methoxy-2-methyl-1-oxopropan-2-yl)amino)benzoate

Enzalutamide Impurity 68

CAT No: CL-EZL-56 CAS No: 50739-71-4 Mol Wt: 244.1 Mol F: C9H10BrNO2 Inv Status: Custom Synthesis

Chemical Name: N-(4-bromo-2-(hydroxymethyl)phenyl)acetamide

Enzalutamide Impurity 69

CAT No: CL-EZL-57 CAS No: 1242840-35-2 Mol Wt: 168.2 : 36.5 Mol F: C8H9FN2O : HCl Inv Status: Custom Synthesis

Chemical Name: 5-Amino-2-fluoro-N-methylbenzamide hydrochloride

Enzalutamide Impurity 70

CAT No: CL-EZL-58 CAS No: 2346499-26-9 Mol Wt: 217.3 Mol F: C12H15N3O Inv Status: Custom Synthesis

Chemical Name: 4-((2-Cyanopropan-2-yl)amino)-N-methylbenzamide

Enzalutamide Impurity 71

CAT No: CL-EZL-59 CAS No: 3035510-37-0 Mol Wt: 483.4 Mol F: C21H17F4N3O4S Inv Status: Custom Synthesis

Chemical Name: 4-(3-(3-fluoro-4-(methylcarbamoyl)phenyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzoic acid

Enzalutamide Impurity 72

CAT No: CL-EZL-60 CAS No: 1332524-02-3 Mol Wt: 241.2 Mol F: C11H12FNO4 Inv Status: Custom Synthesis

Chemical Name: 4-((2-Carboxypropan-2-yl)amino)-2-fluorobenzoic acid

Enzalutamide Impurity 73

CAT No: CL-EZL-61 CAS No: NA Mol Wt: 268.3 Mol F: C13H17FN2O3 Inv Status: Custom Synthesis

Chemical Name: 2-((4-(Dimethylcarbamoyl)-3-fluorophenyl)amino)-2-methylpropanoic acid

Enzalutamide Impurity 74

CAT No: CL-EZL-62 CAS No: 1440965-03-6 Mol Wt: 250 Mol F: C8H6BrF2NO Inv Status: Custom Synthesis

Chemical Name: 4-Bromo-2,6-difluoro-N-methylbenzamide

Enzalutamide Impurity 75

CAT No: CL-EZL-63 CAS No: NA Mol Wt: 281.3 Mol F: C14H16FNO4 Inv Status: Custom Synthesis

Chemical Name: 4-((1-(allyloxy)-2-methyl-1-oxopropan-2-yl)amino)-2-fluorobenzoic acid

Enzalutamide Impurity 76

CAT No: CL-EZL-64 CAS No: NA Mol Wt: 281.3 Mol F: C14H16FNO4 Inv Status: Custom Synthesis

Chemical Name: 2-((4-((allyloxy)carbonyl)-3-fluorophenyl)amino)-2-methylpropanoic acid

Enzalutamide Impurity 77

CAT No: CL-EZL-65 CAS No: 1415552-04-3 Mol Wt: 245.2 Mol F: C9H6F3N3S Inv Status: Custom Synthesis

Chemical Name: 1-(4-Cyano-3-(trifluoromethyl)phenyl)thiourea

Enzalutamide Impurity 78

CAT No: CL-EZL-66 CAS No: 392-09-6 Mol Wt: 199.1 Mol F: C8H6FNO4 Inv Status: Custom Synthesis

Chemical Name: Methyl 2-fluoro-4-nitrobenzoate

Type:Impurity Reference Standard

Total Products: 64

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Enzalutamide Related Products

Enzalutamide is an androgen receptor inhibitor used in the treatment of metastatic castration-resistant prostate cancer. It works by binding to androgen receptors and inhibiting androgen signaling, which is necessary for the growth of prostate cancer cells.

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