Impurity Reference Standard - Products

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Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Diltiazem and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Diltiazem impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Diltiazem-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

Diltiazem EP Impurity C

CAT No: CL-DTZ-02 CAS No: 84903-78-6 Mol Wt: 400.49 Mol F: C21H24N2O4S Inv Status: Custom Synthesis

Chemical Name: (2S,3S)-5-(2-(Dimethylamino)ethyl)-2-(4 -hydroxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl Acetate

Diltiazem EP Impurity B

CAT No: CL-DTZ-03 CAS No: 87447-47-0 Mol Wt: 343.4 Mol F: C18H17NO4S Inv Status: In Stock

Chemical Name: (2S,3S)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate

Diltiazem EP Impurity F

CAT No: CL-DTZ-04 CAS No: 42399-40-6 Mol Wt: 372.5 Mol F: C20H24N2O3S Inv Status: In Stock

Chemical Name: (2S,3S)-5-[2-(dimethylamino)ethyl]-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one

Diltiazem EP Impurity E

CAT No: CL-DTZ-05 CAS No: 42399-49-5 Mol Wt: 301.4 Mol F: C16H15NO3S Inv Status: In Stock

Chemical Name: (2S,3S)-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one

Diltiazem Impurity-8

CAT No: CL-DTZ-06 CAS No: 42399-48-4 Mol Wt: 319.4 Mol F: C16H17NO4S Inv Status: In Stock

Chemical Name: (2S,3S)-3-((2-Aminophenyl)thio)-2-hydroxy-3-(4-methoxyphenyl)propanoic acid

Deacetyl O-Demethyl Diltiazem

CAT No: CL-DTZ-07 CAS No: 84903-82-2 Mol Wt: 358.5 Mol F: C19H22N2O3S Inv Status: Custom Synthesis

Chemical Name: (2S,3S)-5-(2-(Dimethylamino)ethyl)-3-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one

Desacetyl N, O-Didesmethyl Diltiazem

CAT No: CL-DTZ-08 CAS No: 86408-42-6 Mol Wt: 344.4 Mol F: C18H20N2O3S Inv Status: Custom Synthesis

Chemical Name: 1,?5-?Benzothiazepin-?4(5H)?-?one, 2,?3-?dihydro-?3-?hydroxy-?2-?(4-?hydroxyphenyl)?-?5-?[2-?(methylamino)?ethyl]?-?, (2S,?3S)?-

Diltiazem EP Impurity A

CAT No: CL-DTZ-09 CAS No: 111188-71-7 Mol Wt: 414.5 Mol F: C22H26N2O4S Inv Status: Custom Synthesis

Chemical Name: (2R,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate

Diltiazem EP Impurity D

CAT No: CL-DTZ-10 CAS No: 130606-60-9 Mol Wt: 400.5 : 36.5 Mol F: C21H24N2O4S : HCl Inv Status: Custom Synthesis

Chemical Name: (2S,3S)-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate hydrochloride

Diltiazem EP Impurity G

CAT No: CL-DTZ-11 CAS No: 81353-09-5 Mol Wt: 358.5 Mol F: C19H22N2O3S Inv Status: Custom Synthesis

Chemical Name: (2S,3S)-5-[2-(Methylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-ol

Diltiazem HCl

CAT No: CL-DTZ-12 CAS No: 33286-22-5 Mol Wt: 414.5 : 36.5 Mol F: C22H26N2O4S : HCl Inv Status: Custom Synthesis

Chemical Name: Hydrochloride of (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate

Diltiazem N-Oxide

CAT No: CL-DTZ-13 CAS No: 142843-04-7 Mol Wt: 430.5 Mol F: C22H26N2O5S Inv Status: Custom Synthesis

Chemical Name: (2S-cis)-3-(Acetyloxy)-5-[2-(dimethyloxidoamino)ethyl]-2,3-dihydro-2-(4- methoxyphenyl)-1,5-benzothiazepin-4(5H)-one

Diltiazem N-Oxide O-Desacetyl Impurity

CAT No: CL-DTZ-14 CAS No: 122619-90-3 Mol Wt: 388.5 Mol F: C20H24N2O4S Inv Status: Custom Synthesis

Chemical Name: (2S,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-ol N-Oxide

Diltiazem O-Desacetyl-O-Desmethyl HCl

CAT No: CL-DTZ-15 CAS No: 96252-32-3 Mol Wt: 358.5 : 36.5 Mol F: C19H22N2O3S : HCl Inv Status: Custom Synthesis

Chemical Name: (2S,3S)-5-[2-(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride

Diltiazem USP Related Compound H

CAT No: CL-DTZ-16 CAS No: NA Mol Wt: 330.4 : 80.9 Mol F: C17H18N2O3S : HBr Inv Status: Custom Synthesis

Chemical Name: (2S,3S)-5-(2-Aminoethyl)-3-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1,5-benzothiazepine-4(5H)-one

Diltiazem USP Related Compound G

CAT No: CL-DTZ-17 CAS No: NA Mol Wt: 358.5 Mol F: C19H22N2O3S Inv Status: Custom Synthesis

Chemical Name: (2S,3S)-3-Hydroxy-2-(3-methoxyphenyl)-5-[2-(methylamino)ethyl]-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one

Type:Impurity Reference Standard

Total Products: 16

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