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Dasatinib is a tyrosine kinase inhibitor used to treat chronic myelogenous leukemia (CML) and acute lymphoblastic leukemia (ALL) with the Philadelphia chromosome. It inhibits BCR-ABL and SRC family kinases. Dasatinib can be effective in patients resistant to imatinib.

Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Dasatinib and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Dasatinib impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Dasatinib-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

Dasatinib

CAT No: CL-DSA-01 CAS No: 302962-49-8 Mol Wt: 488 Mol F: C22H26ClN7O2S Inv Status: In Stock

Chemical Name: N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide

Dasatinib Carboxylic Acid

CAT No: CL-DSA-02 CAS No: 910297-53-9 Mol Wt: 502 Mol F: C22H24ClN7O3S Inv Status: Custom Synthesis

Chemical Name: 4-[6-[[5-[[(2-Chloro-6-methylphenyl)amino]carbonyl]-2-thiazolyl]amino]-2-methyl-4-pyrimidinyl]-1-piperazineacetic acid

Dasatinib Carboxylic Acid Ethyl Ester

CAT No: CL-DSA-03 CAS No: 910297-62-0 Mol Wt: 530 Mol F: C24H28ClN7O3S Inv Status: Custom Synthesis

Chemical Name: 4-[6-[[5-[[(2-Chloro-6-methylphenyl)amino]carbonyl]-2-thiazolyl]amino]-2-methyl-4-pyrimidinyl]-1-piperazineacetic acid ethyl ester

Dasatinib Dichloro Impurity

CAT No: CL-DSA-04 CAS No: 302964-08-5 Mol Wt: 394.3 Mol F: C16H13ClN5OS Inv Status: Custom Synthesis

Chemical Name: N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide

Dasatinib N-Deshydroxyethyl Impurity

CAT No: CL-DSA-05 CAS No: 910297-51-7 Mol Wt: 444 Mol F: C20H22ClN7OS Inv Status: Custom Synthesis

Chemical Name: N-(2-Chloro-6-methylphenyl)-2-[[2-methyl-6-(1-piperazinyl)-4-pyrimidinyl] amino]-5-thiazolecarboxamide

Dasatinib N-Oxide

CAT No: CL-DSA-06 CAS No: 910297-52-8 Mol Wt: 504 Mol F: C22H26ClN7O3S Inv Status: Custom Synthesis

Chemical Name: 4-(6-(5-(2-Chloro-6-methyl phenyl carbamoyl)thiazole-2-ylamino)-2-methylpyrimidine-4-yl)-1-(2-hydroxy ethyl)piperazine 1-oxide

Dasatinib Dimer Impurity

CAT No: CL-DSA-07 CAS No: 910297-61-9 Mol Wt: 801.8 Mol F: C36H34Cl2N12O2S2 Inv Status: Custom Synthesis

Chemical Name: 2,2'-((Piperazine-1,4-diylbis(2-methylpyrimidine-6,4-diyl))bis(azanediyl))bis(N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide)

Dasatinib Impurity 1

CAT No: CL-DSA-08 CAS No: 2468737-89-3 Mol Wt: 522.5 Mol F: C22H25Cl2N7O2S Inv Status: Custom Synthesis

Chemical Name: N-(2,4-Dichloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)-2-methylpiperazin-1-yl)pyrimidin-4-yl)amino)thiazole-5-carboxamide

Dasatinib Impurity 2

CAT No: CL-DSA-09 CAS No: 302964-24-5 Mol Wt: 267.7 Mol F: C11H10ClN3OS Inv Status: Custom Synthesis

Chemical Name: 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide

Dasatinib Impurity 4

CAT No: CL-DSA-10 CAS No: 1184919-23-0 Mol Wt: 453.6 Mol F: C22H27N7O2S Inv Status: Custom Synthesis

Chemical Name: 2-((6-(4-(2-Hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)-N-(o-tolyl)thiazole-5-carboxamide

Dasatinib Impurity 5

CAT No: CL-DSA-11 CAS No: 1245157-85-0 Mol Wt: 530 Mol F: C24H28ClN7O3S Inv Status: Custom Synthesis

Chemical Name: 2-(4-(6-((5-((2-chloro-6-methylphenyl)carbamoyl)thiazol-2-yl)amino)-2-methylpyrimidin-4-yl)piperazin-1-yl)ethyl acetate

Dasatinib Impurity 6

CAT No: CL-DSA-12 CAS No: 2468737-75-7 Mol Wt: 521.5 Mol F: C23H26Cl2N6O2S Inv Status: Custom Synthesis

Chemical Name: N-(3,6-Dichloro-2-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)methyl)thiazole-5-carboxamide

Dasatinib Impurity 7

CAT No: CL-DSA-13 CAS No: 2468737-76-8 Mol Wt: 522.5 Mol F: C22H25Cl2N7O2S Inv Status: Custom Synthesis

Chemical Name: N-(2,3-Dichloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide

Dasatinib Impurity 8

CAT No: CL-DSA-14 CAS No: 1184914-03-1 Mol Wt: 233.3 Mol F: C11H11N3OS Inv Status: Custom Synthesis

Chemical Name: 2-Amino-N-(o-tolyl)thiazole-5-carboxamide

Dasatinib Impurity 9

CAT No: CL-DSA-15 CAS No: 2468737-77-9 Mol Wt: 302.2 Mol F: C11H9Cl2N3OS Inv Status: Custom Synthesis

Chemical Name: 2-Amino-N-(2,4-dichloro-6-methylphenyl)thiazole-5-carboxamide

Dasatinib Impurity 10

CAT No: CL-DSA-16 CAS No: 2468737-78-0 Mol Wt: 302.2 Mol F: C11H9Cl2N3OS Inv Status: Custom Synthesis

Chemical Name: 2-Amino-N-(2,3-dichloro-6-methylphenyl)thiazole-5-carboxamide

Dasatinib Impurity 11

CAT No: CL-DSA-17 CAS No: 2468737-79-1 Mol Wt: 302.2 Mol F: C11H9Cl2N3OS Inv Status: Custom Synthesis

Chemical Name: 2-Amino-N-(3,6-dichloro-2-methylphenyl)thiazole-5-carboxamide

Dasatinib Impurity 12

CAT No: CL-DSA-18 CAS No: 910297-57-3 Mol Wt: 504 Mol F: C22H26ClN7O3S Inv Status: Custom Synthesis

Chemical Name: N-(2-Chloro-4-hydroxy-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide

Dasatinib Impurity 13

CAT No: CL-DSA-20 CAS No: 1159977-25-9 Mol Wt: 469.6 Mol F: C22H27N7O3S Inv Status: Custom Synthesis

Chemical Name: N-(2-Hydroxy-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide

Dasatinib Impurity 14

CAT No: CL-DSA-21 CAS No: 910297-71-1 Mol Wt: 410.3 Mol F: C16H13Cl2N5O2S Inv Status: Custom Synthesis

Chemical Name: 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-(hydroxymethyl)phenyl)thiazole-5-carboxamide

Dasatinib Impurity 15

CAT No: CL-DSA-22 CAS No: 910297-70-0 Mol Wt: 494.4 Mol F: C21H21Cl2N5O3S Inv Status: Custom Synthesis

Chemical Name: 3-Chloro-2-(2-((6-chloro-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamido)benzyl pivalate

Dasatinib Impurity 16

CAT No: CL-DSA-23 CAS No: 910297-58-4 Mol Wt: 504 Mol F: C22H26ClN7O3S Inv Status: Custom Synthesis

Chemical Name: N-(2-Chloro-6-(hydroxymethyl)phenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide

Dasatinib Impurity 18

CAT No: CL-DSA-24 CAS No: 1860069-15-3 Mol Wt: 664.1 Mol F: C28H34ClN7O8S Inv Status: Custom Synthesis

Chemical Name: (2S,3S,4S,5R,6R)-6-(2-(4-(6-((5-((2-chloro-6-methylphenyl)carbamoyl)thiazol-2-yl)amino)-2-methylpyrimidin-4-yl)piperazin-1-yl)ethoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

Dasatinib Impurity E

CAT No: CL-DSA-25 CAS No: 1159977-13-5 Mol Wt: 544.1 Mol F: C25H30ClN7O3S Inv Status: Custom Synthesis

Chemical Name: Tert-butyl 4-(6-((5-((2-chloro-6-methylphenyl)carbamoyl)thiazol-2-yl)amino)-2-methylpyrimidin-4-yl)piperazine-1-carboxylate

N-Des Hydroxy Ethyl N-Oxide

CAT No: CL-DSA-26 CAS No: 910297-52-8 Mol Wt: 504 Mol F: C22H26ClN7O3S Inv Status: Custom Synthesis

Chemical Name: 4-(6-(5-(2-Chloro-6-methyl phenyl carbamoyl)thiazole-2-ylamino)-2-methylpyrimidine-4-yl)-1-(2-hydroxy ethyl)piperazine 1-oxide

Dasatinib Impurity 21

CAT No: CL-DSA-27 CAS No: NA Mol Wt: 267.7 Mol F: C11H10ClN3OS Inv Status: Custom Synthesis

Chemical Name: 2-Amino-N-(4-chloro-2-methylphenyl)thiazole-5-carboxamide

Dasatinib Impurity 22

CAT No: CL-DSA-28 CAS No: 2518438-16-7 Mol Wt: 309.8 Mol F: C13H12ClN3O2S Inv Status: Custom Synthesis

Chemical Name: 2-Acetamido-N-(2-chloro-6-methylphenyl) thiazole-5-carboxamide

Dasatinib Impurity 23

CAT No: CL-DSA-29 CAS No: NA Mol Wt: 363.7 Mol F: C13H9ClF3N3O2S Inv Status: Custom Synthesis

Chemical Name: N-(2-Chloro-6-methylphenyl)-2-(2,2,2,-trifluoroacetamido)thiazole-5-carboxamide

Dasatinib Monohydrate

CAT No: CL-DSA-30 CAS No: 863127-77-9 Mol Wt: 0.00576388888888889 Mol F: C22H26ClN7O2S : H2O Inv Status: Custom Synthesis

Chemical Name: N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide hydrate

Dasatinib Impurity 24

CAT No: CL-DSA-31 CAS No: 1025814-13-4 Mol Wt: 462 Mol F: C20H24ClN7O2S Inv Status: Custom Synthesis

Chemical Name: N-(2-Chloro-6-methylphenyl)-2-((6-((2-((2-hydroxyethyl)amino)ethyl)amino)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide

Des-2-(Piperazin-1-yl) 2-Amino Dasatinib

CAT No: CL-DSA-32 CAS No: 302962-47-6 Mol Wt: 418.9 Mol F: C18H19ClN6O2S Inv Status: Custom Synthesis

Chemical Name: N-(2-Chloro-6-methylphenyl)-2-((6-((2-hydroxyethyl)amino)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide

Dasatinib Hydrolytic Impurity

CAT No: CL-DSA-33 CAS No: 1245157-42-9 Mol Wt: 364.4 Mol F: C15H20N6O3S Inv Status: Custom Synthesis

Chemical Name: 2-((6-(4-(2-Hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxylic acid

Dasatinib Impurity 27

CAT No: CL-DSA-34 CAS No: 1111850-50-0 Mol Wt: 268.1 Mol F: C12H11Cl2N3 Inv Status: Custom Synthesis

Chemical Name: 6-Chloro-N-(2-chloro-6-methylphenyl)-2-methylpyrimidin-4-amine

Dasatinib Impurity 28

CAT No: CL-DSA-35 CAS No: 2099694-51-4 Mol Wt: 289.5 Mol F: C10H7Cl3N4 Inv Status: Custom Synthesis

Chemical Name: 4,6-Dichloro-2-((6-chloro-2-methylpyrimidin-4-yl)methyl)pyrimidine

Dasatinib Impurity 29

CAT No: CL-DSA-36 CAS No: 2099694-52-5 Mol Wt: 476.6 Mol F: C21H32N8O3S Inv Status: Custom Synthesis

Chemical Name: (4-(2-Hydroxyethyl)piperazin-1-yl)(2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazol-5-yl)methanone

Dasatinib Impurity 30

CAT No: CL-DSA-37 CAS No: 2468737-80-4 Mol Wt: 625.5 Mol F: C27H22Cl2N8O2S2 Inv Status: Custom Synthesis

Chemical Name: 2,2'-((2-Methylpyrimidine-4,6-diyl)bis(azanediyl))bis(N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide)

Dasatinib Impurity 31

CAT No: CL-DSA-38 CAS No: NA Mol Wt: 361.5 Mol F: C17H23N5O2S Inv Status: Custom Synthesis

Chemical Name: 2-Amino-N-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-6-methylphenyl)thiazole-5-carboxamide

Dasatinib Impurity 32

CAT No: CL-DSA-39 CAS No: 2468737-87-1 Mol Wt: 581.7 Mol F: C28H39N9O3S Inv Status: Custom Synthesis

Chemical Name: 2-((6-(4-(2-Hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)-N-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-6-methylphenyl)thiazole-5-carboxamide

Dasatinib Impurity 33

CAT No: CL-DSA-40 CAS No: 1180525-74-9 Mol Wt: 520.8 Mol F: C21H16Cl3N7OS Inv Status: Custom Synthesis

Chemical Name: 2-(Bis(6-chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide

Dasatinib Impurity 34

CAT No: CL-DSA-41 CAS No: NA Mol Wt: 339.8 Mol F: C13H10ClN3O4S Inv Status: Custom Synthesis

Chemical Name: 2-((5-((2-Chloro-6-methylphenyl)carbamoyl)thiazol-2-yl)amino)-2-oxoacetic acid

Dasatinib Impurity 35

CAT No: CL-DSA-42 CAS No: 2167236-23-7 Mol Wt: 202.2 Mol F: C6H6N2O4S Inv Status: Custom Synthesis

Chemical Name: 2-((Methoxycarbonyl)amino)thiazole-5-carboxylic acid

Dasatinib Impurity 36

CAT No: CL-DSA-43 CAS No: 302964-20-1 Mol Wt: 262.7 Mol F: C9H11ClN2O3S Inv Status: Custom Synthesis

Chemical Name: Tert-butyl (5-(chlorocarbonyl)thiazol-2-yl)carbamate

Dasatinib Impurity 37

CAT No: CL-DSA-44 CAS No: 302964-06-3 Mol Wt: 367.8 Mol F: C16H18ClN3O3S Inv Status: Custom Synthesis

Chemical Name: Tert-butyl (5-((2-chloro-6-methylphenyl)carbamoyl)thiazol-2-yl)carbamate

Dasatinib Impurity 38

CAT No: CL-DSA-45 CAS No: NA Mol Wt: 463.3 Mol F: C20H16Cl2N4O3S Inv Status: Custom Synthesis

Chemical Name: N1-(2-Chloro-6-methylphenyl)-N2-(5-((2-chloro-6-methylphenyl)carbamoyl)thiazol-2-yl)oxalamide

Dasatinib Impurity 39

CAT No: CL-DSA-46 CAS No: 2641759-50-2 Mol Wt: 552 Mol F: C24H27ClFN5O5S Inv Status: Custom Synthesis

Chemical Name: 4-((4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)amino)-4-oxo-1-(piperidin-1-yl)butane-2-sulfonic acid

Dasatinib Impurity 40

CAT No: CL-DSA-47 CAS No: 2468737-83-7 Mol Wt: 488 Mol F: C22H26ClN7O2S Inv Status: Custom Synthesis

Chemical Name: N-(2-Chloro-6-methylphenyl)-2-((2-methyl-6-(2-(piperazin-1-yl)ethoxy)pyrimidin-4-yl)amino)thiazole-5-carboxamide

Dasatinib Impurity 41

CAT No: CL-DSA-48 CAS No: 2468737-81-5 Mol Wt: 394.3 Mol F: C16H13Cl2N5OS Inv Status: Custom Synthesis

Chemical Name: 2-Amino-N-(6-chloro-2-methylpyrimidin-4-yl)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide

Dasatinib Impurity 42

CAT No: CL-DSA-49 CAS No: 1417651-54-7 Mol Wt: 506.8 Mol F: C21H18Cl3N7S Inv Status: Custom Synthesis

Chemical Name: N-(6-Chloro-2-methylpyrimidin-4-yl)-5-(((6-chloro-2-methylpyrimidin-4-yl)(2-chloro-6-methylphenyl)amino)methyl)thiazol-2-amine

Dasatinib-d4

CAT No: CL-DSA-50 CAS No: 1160297-08-4 Mol Wt: 492 Mol F: C22H22D4ClN7O2S Inv Status: Custom Synthesis

Chemical Name: N-(2-Chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl-1,1,2,2-d4)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide

Dasatinib D8

CAT No: CL-DSA-51 CAS No: 1132093-70-9 Mol Wt: 496.1 Mol F: C22H18D8ClN7O2S Inv Status: Custom Synthesis

Chemical Name: N-(2-Chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl-2,2,3,3,5,5,6,6-d8)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide

Dasatinib D8 N-Oxide

CAT No: CL-DSA-52 CAS No: 1189988-36-0 Mol Wt: 512.1 Mol F: C22H18D8ClN7O3S Inv Status: Custom Synthesis

Chemical Name: 4-(6-((5-((2-Chloro-6-methylphenyl)carbamoyl)thiazol-2-yl)amino)-2-methylpyrimidin-4-yl)-1-(2-hydroxyethyl)piperazine 1-oxide-2,2,3,3,5,5,6,6-d8

N-Boc-N-Deshydroxyethyl Dasatinib D8

CAT No: CL-DSA-53 CAS No: 1263379-04-9 Mol Wt: 552.1 Mol F: C25H22D8ClN7O3S Inv Status: Custom Synthesis

Chemical Name: Tert-butyl 4-(6-((5-((2-chloro-6-methylphenyl)carbamoyl)thiazol-2-yl)amino)-2-methylpyrimidin-4-yl)piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d8

Acetamidine Hydrochloride

CAT No: CL-DSA-54 CAS No: 124-42-5 Mol Wt: 94.54 Mol F: C2H6N2?HCl Inv Status: In Stock

Chemical Name: Acetamidine Hydrochloride

Type:Impurity Reference Standard

Total Products: 53

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Dasatinib Related Products

Dasatinib is a tyrosine kinase inhibitor used to treat chronic myelogenous leukemia (CML) and acute lymphoblastic leukemia (ALL) with the Philadelphia chromosome. It inhibits BCR-ABL and SRC family kinases. Dasatinib can be effective in patients resistant to imatinib.

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