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Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Cyclosporin and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Cyclosporin impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Cyclosporin-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

Cyclosporin

CAT No: CL-CLPN-01 CAS No: 59865-13-3 Mol Wt: 1202.6 Mol F: C62H111N11O12 Inv Status: In Stock

Chemical Name: Cyclosporin A

Cyclosporin A Dihydro Impurity

CAT No: CL-CLPN-02 CAS No: 59865-15-5 Mol Wt: 1204.6 Mol F: C62H113N11O12 Inv Status: Custom Synthesis

Chemical Name: 6-[(2S,3R,4R)-3-Hydroxy-4-methyl-2-(methylamino)octanoic acid]cyclosporin A

Cyclosporin A Isomer

CAT No: CL-CLPN-03 CAS No: 59865-16-6 Mol Wt: 1202.6 Mol F: C62H111N11O12 Inv Status: Custom Synthesis

Chemical Name: O3.1,11-anhydro[(2S,3R,4R,6E)-3-hydroxy-4-m?thyl-2-(m?thylamino)oct-6-?noyl-(2S)-2-aminobutanoyl-N-m?thylglycyl-N-m?thyl-L-leucyl-L-valyl-N-m?thyl-L-leucyl-L-alanyl-D-alanyl-N-m?thyl-L-leucyl-N-m?thyl-L-leucyl-N-m?thyl-L-valine]

Cyclosporin B

CAT No: CL-CLPN-04 CAS No: 63775-95-1 Mol Wt: 1188 Mol F: C61H109N11O12 Inv Status: Custom Synthesis

Chemical Name: Cyclosporin B

Cyclosporin C

CAT No: CL-CLPN-05 CAS No: 59787-61-0 Mol Wt: 1218.6 Mol F: C62H111N11O13 Inv Status: Custom Synthesis

Chemical Name: Cyclosporin C

Cyclosporin D

CAT No: CL-CLPN-06 CAS No: 63775-96-2 Mol Wt: 1214.6 Mol F: C63H111N11O12 Inv Status: Custom Synthesis

Chemical Name: Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-threonyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl] ;

Cyclosporin H

CAT No: CL-CLPN-07 CAS No: 83602-39-5 Mol Wt: 1202.6 Mol F: C62H111N11O12 Inv Status: Custom Synthesis

Chemical Name: (3R,6S,9S,12R,15S,18S,21S,24S,30S,33S,34R)-30-ethyl-34-((R,E)-hex-4-en-2-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-4,7,10,12,15,19,25,28-octamethyl-33-(methylamino)-1-oxa-4,7,10,13,16,19,22,25,28,31-decaazacyclotetratriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone

Isocyclosporin H

CAT No: CL-CLPN-08 CAS No: 83602-43-1 Mol Wt: 1202.6 Mol F: C62H111N11O12 Inv Status: Custom Synthesis

Chemical Name: Cyclosporin U

Cyclosporine U

CAT No: CL-CLPN-09 CAS No: 108027-45-8 Mol Wt: 1188.6 Mol F: C61H109N11O12 Inv Status: Custom Synthesis

Chemical Name: 1,11-anhydro[L-alanyl-D-alanyl-N-m?thyl-L-leucyl-N-m?thyl-L-leucyl-N-m?thyl-L-valyl-(2S,3R,4R,6E)-3-hydroxy-4-m?thyl-2-(m?thylamino)oct-6-?noyl-(2S)-2-aminobutanoyl-N-m?thylglycyl-N-m?thyl-L-leucyl-L-valyl-L-leucine]

Cyclosporin G

CAT No: CL-CLPN-10 CAS No: 74436-00-3 Mol Wt: 1202.6 Mol F: C62H111N11O12 Inv Status: Custom Synthesis

Chemical Name: Cyclosporin G

Cyclosporine L

CAT No: CL-CLPN-11 CAS No: 108027-39-0 Mol Wt: 1188.6 Mol F: C61H109N11O12 Inv Status: Custom Synthesis

Chemical Name: Cyclosporin L

Cyclosporin V

CAT No: CL-CLPN-12 CAS No: 108027-46-9 Mol Wt: 1216.7 Mol F: C63H113N11O12 Inv Status: Custom Synthesis

Chemical Name: Abu1-ciclosporin A; 1,11-Anhydro[D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-N-methyl-L-[(1S,N-methyl-Lleucyl-L-valyl-N-methyl-L-leucyl-L-2-aminobutanoic acid]; 1,11-anhydro[D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-[(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-(2S)-2-aminobutanoic acid];

Cyclosporin Impurity 1

CAT No: CL-CLPN-13 CAS No: 437611-17-1 Mol Wt: 1188.6 Mol F: C61H109N11O12 Inv Status: Custom Synthesis

Chemical Name: (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-21,30-diethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3-isopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone

Cyclosporin EP Impurity F

CAT No: CL-CLPN-14 CAS No: NA Mol Wt: 1202.6 Mol F: C62H111N11O12 Inv Status: Custom Synthesis

Chemical Name: 1,11-Anhydro[L-alanyl-D-alanyl-N-m?thyl-L-leucyl-N-m?thyl-L-leucyl-N-m?thyl-L-valyl-(2S,3R,4R,6E)-3-hydroxy-4-m?thyl-2-(m?thylamino)oct-6-?noyl-(2S)-2-aminobutanoyl-N-m?thylglycyl-N-m?thyl-L-leucyl-(2S)-2-aminobutanoyl-N-m?thyl-L-leucine]

Cyclosporin Impurity 2

CAT No: CL-CLPN-15 CAS No: 1907654-63-0 Mol Wt: 1146.5 Mol F: C58H103N11O12 Inv Status: Custom Synthesis

Chemical Name: (4S,5R)-5-((R,E)-Hex-4-en-2-yl)-3-methyl-2-oxo-N-((4S,7S,10R,13S,16S,19S,22S,28S)-4,7,16,22-tetraisobutyl-19-isopropyl-5,8,10,13,17,23,26-heptamethyl-3,6,9,12,15,18,21,24,27-nonaoxo-2,5,8,11,14,17,20,23,26-nonaazatriacontan-28-yl)oxazolidine-4-carboxamide

Cyclosporin E

CAT No: CL-CLPN-16 CAS No: 63798-73-2 Mol Wt: 1188.6 Mol F: C61H109N11O12 Inv Status: Custom Synthesis

Chemical Name: (3S,6R,9S,12S,15S,18S,24S,27S,30S,33S)-24-ethyl-27-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-3,12,18,33-tetraisobutyl-15,30-diisopropyl-1,4,6,9,13,19,22,28-octamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone

Cyclosporin AM 1

CAT No: CL-CLPN-17 CAS No: 89270-28-0 Mol Wt: 1218.6 Mol F: C62H111N11O13 Inv Status: Custom Synthesis

Chemical Name: (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-((1R,2R,E)-1,6-Dihydroxy-2-methylhex-4-en-1-yl)-30-ethyl-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone

Cyclosporin AM 9

CAT No: CL-CLPN-18 CAS No: 89270-25-7 Mol Wt: 1218.6 Mol F: C62H111N11O13 Inv Status: Custom Synthesis

Chemical Name: (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-9-(2-hydroxy-2-methylpropyl)-6,18,24-triisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone

Acetyl-Cyclosporin A Aldehyde

CAT No: CL-CLPN-20 CAS No: 121584-52-9 Mol Wt: 1232.6 Mol F: C62H109N11O14 Inv Status: Custom Synthesis

Chemical Name: (1R,2R)-1-((2S,5S,11S,14S,17S,20S,23R,26S,29S,32S)-5-ethyl-11,17,26,29-tetraisobutyl-14,32-diisopropyl-1,7,10,16,20,23,25,28,31-nonamethyl-3,6,9,12,15,18,21,24,27,30,33-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2-yl)-2-methyl-4-oxobutyl acetate

Cyclosporin EP Impurity G

CAT No: CL-CLPN-21 CAS No: 63775-96-2 Mol Wt: 1214.6 Mol F: C63H111N11O12 Inv Status: Custom Synthesis

Chemical Name: 1,11-Anhydro[L-alanyl-D-alanyl-N-m?thyl-L-leucyl-N-m?thyl-L-leucyl-N-m?thyl-L-valyl-(2S,3R,4R,6E)-3-hydroxy-4-m?thyl-2-(m?thylamino)oct-6-?noyl-L-valyl-N-m?thylglycyl-N-m?thyl-L-leucyl-L-valyl-N-m?thyl-L-leucine]

Cyclosporin T

CAT No: CL-CLPN-22 CAS No: 108027-44-7 Mol Wt: 1188.6 Mol F: C61H109N11O12 Inv Status: Custom Synthesis

Chemical Name: (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,10,12,15,19,25,28-octamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone

Dehydro Cyclosporin

CAT No: CL-CLPN-23 CAS No: NA Mol Wt: 1196.6 Mol F: C63H109N11O11 Inv Status: Custom Synthesis

Chemical Name: (3S,6S,9S,12R,15S,18S,21S,30S,E)-30-ethyl-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-33-((R,E)-2-methylhepta-4,6-dien-1-ylidene)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone

Cyclosporin EP Impurity D

CAT No: CL-CLPN-24 CAS No: 108027-45-8 Mol Wt: 1188.6 Mol F: C61H109N11O12 Inv Status: Custom Synthesis

Cyclosporin EP Impurity E

CAT No: CL-CLPN-25 CAS No: 108027-46-9 Mol Wt: 1216.7 Mol F: C63H113N11O12 Inv Status: Custom Synthesis

Chemical Name: 1,11-Anhydro[acide?D-alanyl-N-m?thyl-L-leucyl-N-m?thyl-L-leucyl-N-m?thyl-L-valyl-(2S,3R,4R,6E)-3-hydroxy-4-m?thyl-2-(m?thylamino)oct-6-?noyl-(2S)-2-aminobutanoyl-N-m?thylglycyl-N-m?thyl-L-leucyl-L-valyl-N-m?thyl-L-leucyl-(2S)-2-aminobutano?que]

Cyclosporin A D4

CAT No: CL-CLPN-26 CAS No: NA Mol Wt: 1206.7 Mol F: C62H107D4N11O12 Inv Status: Custom Synthesis

Chemical Name: (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,Z)-1-hydroxy-2-methylhex-4-en-1-yl-5,6,6,6-d4)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone

Type:Impurity Reference Standard

Total Products: 25

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