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Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Clobetasone Butyrate and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Clobetasone Butyrate impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Clobetasone Butyrate-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

Clobetasone Butyrate
CAT No: CL-CTBR-01 CAS No: 25122-57-0 Mol Wt: 479 Mol F: C26H32ClFO5 Inv Status: Custom Synthesis
Chemical Name: 21-Chloro-9-fluoro-16?-methyl-3,11,20-trioxopregna-1,4-dien-17-yl butanoate.
Clobetasone Butyrate EP Impurity A
CAT No: CL-CTBR-02 CAS No: 54063-32-0 Mol Wt: 408.9 Mol F: C22H26ClFO4 Inv Status: Custom Synthesis
Chemical Name: 21-Chloro-9-fluoro-17-hydroxy-16?-methylpregna-1,4-diene-3,11,20-trione
Clobetasone Butyrate EP Impurity C
CAT No: CL-CTBR-03 CAS No: 639817-49-5 Mol Wt: 481 Mol F: C26H34ClFO5 Inv Status: Custom Synthesis
Chemical Name:  21-Chloro-9-fluoro-16?-methyl-3,11,20-trioxopregn-1-en-17-yl butanoate; 4,5-dihydroclobetasone butyrate
Clobetasone Butyrate EP Impurity D
CAT No: CL-CTBR-04 CAS No: 639817-51-9 Mol Wt: 557.9 Mol F: C26H31BrClFO5 Inv Status: Custom Synthesis
Chemical Name: 2-Bromo-21-chloro-9-fluoro-16?-methyl-3,11,20-trioxopregna-1,4-dien-17-yl butanoate; 2-bromoclobetasone butyrate
Clobetasone Butyrate EP Impurity E
CAT No: CL-CTBR-05 CAS No: 639817-48-4 Mol Wt: 481 Mol F: C26H34ClFO5 Inv Status: Custom Synthesis
Chemical Name: 21-Chloro-9-fluoro-16?-methyl-3,11,20-trioxopregn-4-en-17-yl butanoate; 1,2-dihydroclobetasone butyrate;
Clobetasone Butyrate EP Impurity F
CAT No: CL-CTBR-06 CAS No: 25120-98-3 Mol Wt: 479 Mol F: C26H32ClFO5 Inv Status: Custom Synthesis
Chemical Name: 21-Chloro-9-fluoro-16?-methyl-3,11,20-trioxopregna-1,4-dien-17-yl butanoate; 16?-methyl clobetasone butyrate;
Clobetasone Butyrate EP Impurity G
CAT No: CL-CTBR-07 CAS No: NA Mol Wt: 516.6 Mol F: C29H37FO7 Inv Status: Custom Synthesis
Chemical Name:  9-Fluoro-16?-methyl-3,11,20-trioxo-21-(propanoyloxy)pregna-1,4-dien-17-yl butanoate,
Clobetasone Butyrate EP Impurity H
CAT No: CL-CTBR-08 CAS No: 25122-56-9 Mol Wt: 465 Mol F: C25H30ClFO5 Inv Status: Custom Synthesis
Chemical Name: 21-Chloro-9-fluoro-16?-methyl-3,11,20-trioxopregna-1,4-dien-17-yl propanoate; 17-O-propionyl clobetasone;
Clobetasone Butyrate EP Impurity I
CAT No: CL-CTBR-09 CAS No: 639817-47-3 Mol Wt: 479 Mol F: C26H32ClFO5 Inv Status: Custom Synthesis
Chemical Name: 21-Chloro-9-fluoro-16?-methyl-3,11,20-trioxopregna-1,4-dien-17-yl 2-methylpropanoate; 17-O-isobutyryl clobetasone
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