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Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Captopril and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Captopril impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Captopril-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

Captopril

CAT No: CL-CPTL-01 CAS No: 62571-86-2 Mol Wt: 217.3 Mol F: C9H15NO3S Inv Status: Custom Synthesis

Chemical Name: (2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid (as per EP) ; 1-[(2S)-3-Mercapto-2-methylpropionyl]-l-proline

Captopril EP Impurity A

CAT No: CL-CPTL-02 CAS No: 64806-05-9 Mol Wt: 432.6 Mol F: C18H28N2O6S2 Inv Status: Custom Synthesis

Chemical Name: 1,1?-[Disulfanediylbis[(2S)-2-methyl-1-oxopropane-3,1-diyl]]bis[(2S)-pyrrolidine-2-carboxylic] acid (as per EP) ; (2?S)-[(2S,2?S)-3,3?-Disulfanediylbis(2-methylpropanoyl)]di-l-proline

Captopril EP Impurity B

CAT No: CL-CPTL-03 CAS No: 80629-35-2 Mol Wt: 264.1 Mol F: C9H14BrNO3 Inv Status: Custom Synthesis

Chemical Name: (2S)-1-[(2S)-3-bromo-2-methylpropanoyl]pyrrolidine-2-carboxylic acid

Captopril EP Impurity C

CAT No: CL-CPTL-04 CAS No: 26473-47-2 Mol Wt: 120.2 Mol F: C4H8O2S Inv Status: Custom Synthesis

Chemical Name: (2RS)-2-methyl-3-sulfanylpropanoic acid

Captopril EP Impurity D

CAT No: CL-CPTL-05 CAS No: 56970-78-6 Mol Wt: 167 Mol F: C4H7BrO2 Inv Status: Custom Synthesis

Chemical Name: (2RS)-3-bromo-2-methylpropanoic acid

Captopril EP Impurity E

CAT No: CL-CPTL-06 CAS No: 23500-15-4 Mol Wt: 185.2 Mol F: C9H15NO3 Inv Status: Custom Synthesis

Chemical Name: (2S)-1-(2-methylpropanoyl)pyrrolidine-2-carboxylic acid

Captopril EP Impurity F

CAT No: CL-CPTL-07 CAS No: 63250-36-2 Mol Wt: 217.3 Mol F: C9H15NO3S Inv Status: Custom Synthesis

Chemical Name: (2S)-1-[(2R)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid

Captopril EP Impurity G

CAT No: CL-CPTL-08 CAS No: 33325-40-5 Mol Wt: 162.2 Mol F: C6H10O3S Inv Status: Custom Synthesis

Chemical Name: (2RS)-3-(acetylsulfanyl)-2-methylpropanoic acid

Captopril EP Impurity H

CAT No: CL-CPTL-09 CAS No: 205521-07-9 Mol Wt: 361.5 Mol F: C15H23NO5S2 Inv Status: Custom Synthesis

Chemical Name: (2S)-1-[(2S)-3-[[(2R)-3-(acetylsulfanyl)-2-methylpropanoyl]sulfanyl]-2-methylpropanoyl]pyrrolidine-2-carboxylicacid

Captopril EP Impurity I

CAT No: CL-CPTL-10 CAS No: NA Mol Wt: 416.6 Mol F: C18H28N2O5S2 Inv Status: Custom Synthesis

Chemical Name: (2S)-1-[(2S)-3-[[[(2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidin-2-yl]carbonyl]sulfanyl]-2-methylpropanoyl]pyrrolidine-2-carboxylic acid

Captopril EP Impurity J

CAT No: CL-CPTL-11 CAS No: 64838-55-7 Mol Wt: 259.3 Mol F: C11H17NO4S Inv Status: Custom Synthesis

Chemical Name: (2S)-1-[(2S)-3-(acetylsulfanyl)-2-methylpropanoyl]pyrrolidine-2-carboxylic acid

Captopril EP Impurity L

CAT No: CL-CPTL-12 CAS No: NA Mol Wt: 446.6 Mol F: C19H30N2O6S2 Inv Status: Custom Synthesis

Chemical Name: 1,1?-[Methylenebis[sulfanediyl[(2S)-2-methyl-1-oxopropane-3,1-diyl]]]bis[(2S)-pyrrolidine-2-carboxylic] acid

Captopril EP Impurity M

CAT No: CL-CPTL-13 CAS No: NA Mol Wt: 335.4 Mol F: C13H21NO5S2 Inv Status: Custom Synthesis

Chemical Name: (2S)-1-[(2S)-3-[[(2S)-2-carboxypropyl]disulfanyl]-2-methylpropanoyl]pyrrolidine-2-carboxylic acid

Captopril EP Impurity N

CAT No: CL-CPTL-14 CAS No: 65134-74-9 Mol Wt: 238.3 Mol F: C8H14O4S2 Inv Status: Custom Synthesis

Chemical Name: 3,3?-Disulfanediylbis[(2S)-2-methylpropanoic] acid

Captopril EP Impurity O

CAT No: CL-CPTL-15 CAS No: NA Mol Wt: 474.6 Mol F: C21H34N2O6S2 Inv Status: Custom Synthesis

Chemical Name: 1,1?-[Propane-2,2-diylbis[sulfanediyl[(2S)-2-methyl-1-oxopropane-3,1-diyl]]]bis[(2S)-pyrrolidine-2-carboxylic]acid

Captopril Methyl Ester

CAT No: CL-CPTL-16 CAS No: 176036-41-2 Mol Wt: 231.3 Mol F: C10H17NO3S Inv Status: Custom Synthesis

Chemical Name: (2S)-1-[(2S)-2-Methyl-3-sulphanylpropanoyl]pyrrolidine-2-carboxylic acid methyl ester

Captopril Ethyl Ester

CAT No: CL-CPTL-17 CAS No: 86938-12-7 Mol Wt: 245.3 Mol F: C11H19NO3S Inv Status: Custom Synthesis

Chemical Name: (2S)-1-[(2S)-2-Methyl-3-sulphanylpropanoyl]pyrrolidine-2-carboxylic acid ethyl ester

Captopril Related Compound 1

CAT No: CL-CPTL-18 CAS No: NA Mol Wt: 365.5 Mol F: C18H23NO5S Inv Status: Custom Synthesis

Chemical Name: ((S)-3-((2-(3-methoxyphenyl)-2-oxoethyl)thio)-2-methylpropanoyl)-L-proline

Captopril Related Compound 2

CAT No: CL-CPTL-19 CAS No: NA Mol Wt: 397.4 Mol F: C16H16F5NO3S Inv Status: Custom Synthesis

Chemical Name: ((S)-2-Methyl-3-(((perfluorophenyl)methyl)thio)propanoyl)-L-proline

Captopril Related Compound 3

CAT No: CL-CPTL-20 CAS No: 185804-96-0 Mol Wt: 342.4 Mol F: C15H22N2O5S Inv Status: Custom Synthesis

Chemical Name: ((2S)-3-((1-ethyl-2,5-dioxopyrrolidin-3-yl)thio)-2-methylpropanoyl)-L-proline

Captopril Related Compound 4

CAT No: CL-CPTL-21 CAS No: 74345-73-6 Mol Wt: 180.7 Mol F: C6H9ClO2S Inv Status: Custom Synthesis

Chemical Name: (R)-S-(3-Chloro-2-methyl-3-oxopropyl) ethanethioate

Captopril Related Compound 5

CAT No: CL-CPTL-22 CAS No: 69570-39-4 Mol Wt: 180.7 Mol F: C6H9ClO2S Inv Status: Custom Synthesis

Chemical Name: (S)-S-(3-Chloro-2-methyl-3-oxopropyl) ethanethioate

Captopril Related Compound 6

CAT No: CL-CPTL-23 CAS No: 65167-28-4 Mol Wt: 259.3 Mol F: C11H17NO4S Inv Status: Custom Synthesis

Chemical Name: ((R)-3-(Acetylthio)-2-methylpropanoyl)-L-proline

Captopril Related Compound 7

CAT No: CL-CPTL-24 CAS No: 112243-88-6 Mol Wt: 217.3 Mol F: C9H15NO3S Inv Status: Custom Synthesis

Chemical Name: ((R)-3-Mercapto-2-methylpropanoyl)-D-proline

Captopril D3

CAT No: CL-CPTL-25 CAS No: 1356383-38-4 Mol Wt: 220.3 Mol F: C9H12D3NO3S Inv Status: Custom Synthesis

Chemical Name: (S)-1-((S)-3-Mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylic-2,5,5-d3 acid

Captopril Related Compound 8

CAT No: CL-CPTL-26 CAS No: 76497-39-7 Mol Wt: 162.2 Mol F: C6H10O3S Inv Status: Custom Synthesis

Chemical Name: (S)-3-(Acetylthio)-2-methylpropanoic acid

D-Captopril

CAT No: CL-CPTL-27 CAS No: 119238-52-7 Mol Wt: 217.3 Mol F: C9H15NO3S Inv Status: Custom Synthesis

Chemical Name: ((S)-3-Mercapto-2-methylpropanoyl)-D-proline

Type:Impurity Reference Standard

Total Products: 27

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