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Type:Impurity Reference Standard
Total Products: 11
Inv. Status:

Caffeine Related Products
Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Caffeine and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Caffeine impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Caffeine-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.
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Caffeine
CAT No: CL-CFN-01 CAS No: 58-08-2 Mol Wt: 194.2 Mol F: C8H10N4O2 Inv Status: Custom Synthesis
Chemical Name: 1,3,7-Trimethyl-3,7-dihydro-1H-purine-2,6-dione ; 1,3,7-Trimethylxanthine ; 7-Methyltheophylline
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Caffeine EP Impurity A
CAT No: CL-CFN-02 CAS No: 58-55-9 Mol Wt: 180.2 Mol F: C7H8N4O2 Inv Status: Custom Synthesis
Chemical Name: 1,3-Dimethyl-3,7-dihydro-1H-purine-2,6-dione
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Caffeine EP Impurity B
CAT No: CL-CFN-03 CAS No: 7597-60-6 Mol Wt: 198.2 Mol F:  C7H10N4O3 Inv Status: Custom Synthesis
Chemical Name: N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)formamide
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Caffeine EP Impurity C
CAT No: CL-CFN-04 CAS No: 519-32-4 Mol Wt: 194.2 Mol F: C8H10N4O2 Inv Status: Custom Synthesis
Chemical Name: 1,3,9-Trimethyl-3,9-dihydro-1H-purine-2,6-dione ; 1,3,9-Trimethylxanthine ; 9-Methyltheophylline
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Caffeine EP Impurity D
CAT No: CL-CFN-05 CAS No: 83-67-0 Mol Wt: 180.2 Mol F: C7H8N4O2 Inv Status: Custom Synthesis
Chemical Name:  3,7-Dimethyl-3,7-dihydro-1H-purine-2,6-dione
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Caffeine EP Impurity E
CAT No: CL-CFN-06 CAS No: 20041-90-1 Mol Wt: 168.2 Mol F: C7H12N4O Inv Status: In Stock
Chemical Name: N,1-Dimethyl-4-(methylamino)-1H-imidazole-5-carboxamide
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Caffeine EP Impurity F
CAT No: CL-CFN-07 CAS No: 611-59-6 Mol Wt: 180.2 Mol F: C7H8N4O2 Inv Status: Custom Synthesis
Chemical Name: 1,7-Dimethyl-3,7-dihydro-1H-purine-2,6-dione ; 1,7-Dimethylxanthine
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Caffeine Impurity 1
CAT No: CL-CFN-08 CAS No: NA Mol Wt: 200.2 Mol F: C7H12N4O3 Inv Status: Custom Synthesis
Chemical Name: 1,3-Dimethyl-4-amino-5-formylaminouracil
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Caffeine Impurity 2
CAT No: CL-CFN-09 CAS No: NA Mol Wt: 197.2 : 23.0 Mol F: C7H9N4O3 : Na Inv Status: Custom Synthesis
Chemical Name: Sodium 4-(1,3-dimethylureido)-1H-imidazole-5-carboxylate
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Caffeine Impurity 3
CAT No: CL-CFN-10 CAS No: 104497-09-8 Mol Wt: 157.2 Mol F: C6H11N3O2 Inv Status: Custom Synthesis
Chemical Name: 6-Amino-1,3-dimethyldihydropyrimidine-2,4(1H,3H)-dione
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Caffeine Impurity 4
CAT No: CL-CFN-11 CAS No: 6642-31-5 Mol Wt: 155.2 Mol F: C6H9N3O2 Inv Status: Custom Synthesis
Chemical Name: 6-Amino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione

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