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Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Avatrombopag and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Avatrombopag impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Avatrombopag-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

Avatrombopag Maleate

CAT No: CL-AVBG-01 CAS No: 677007-74-8 Mol Wt: 649.7 : 116.1 Mol F: C29H34Cl2N6O3S2 : C4H4O4 Inv Status: Custom Synthesis

Chemical Name: 1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid compound with maleic acid (1:1)

Avatrombopag Di Acid Impurity

CAT No: CL-AVBG-02 CAS No: 958457-83-5 Mol Wt: 284.7 Mol F: C12H13ClN2O4 Inv Status: Custom Synthesis

Chemical Name: 6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic acid

Avatrombopag Bromo Acid Impurity

CAT No: CL-AVBG-03 CAS No: NA Mol Wt: 728.5 Mol F: C29H33BrCl2N6O3S2 Inv Status: Custom Synthesis

Chemical Name: 1-(5-((4-(5-Bromo-4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)-3-chloropyridin-2-yl)piperidine-4-carboxylic acid

Avatrombopag Ester Impurity

CAT No: CL-AVBG-04 CAS No: NA Mol Wt: 677.7 : 73.1 Mol F: C31H38Cl2N6O3S2 : C3H7NO Inv Status: Custom Synthesis

Chemical Name: Ethyl 1-(3-chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylate compound with N,N-dimethylformamide (1:1)

Avatrombopag Diamide Impurity

CAT No: CL-AVBG-05 CAS No: NA Mol Wt: 1014.6 Mol F: C46H55Cl3N10O2S4 Inv Status: Custom Synthesis

Chemical Name: 5-Chloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)-6-(4-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)piperidin-1-yl)nicotinamide

Avatrombopag 5-Chloro Acid Impurity

CAT No: CL-AVBG-06 CAS No: NA Mol Wt: 649.7 Mol F: C29H34Cl2N6O3S2 Inv Status: Custom Synthesis

Chemical Name: 1-(3-Chloro-5-((4-(5-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid

Avatrombopag

CAT No: CL-AVBG-07 CAS No: 570406-98-3 Mol Wt: 649.7 Mol F: C29H34Cl2N6O3S2 Inv Status: Custom Synthesis

Chemical Name: 1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid

Avatrombopag N-Oxide Impurity 1

CAT No: CL-AVBG-08 CAS No: NA Mol Wt: 665.6 Mol F: C29H34Cl2N6O4S2 Inv Status: Custom Synthesis

Chemical Name: 1-(2-(6-(4-carboxypiperidin-1-yl)-5-chloronicotinamido)-4-(4-chlorothiophen-2-yl)thiazol-5-yl)-4-cyclohexylpiperazine 1-oxide

Avatrombopag N-Oxide Impurity 2

CAT No: CL-AVBG-09 CAS No: 2681355-40-6 Mol Wt: 665.6 Mol F: C29H34Cl2N6O4S2 Inv Status: Custom Synthesis

Chemical Name: 4-(2-(6-(4-Carboxypiperidin-1-yl)-5-chloronicotinamido)-4-(4-chlorothiophen-2-yl)thiazol-5-yl)-1-cyclohexylpiperazine 1-oxide

Avatrombopag Dimer Impurity 1

CAT No: CL-AVBG-10 CAS No: NA Mol Wt: 819.9 Mol F: C36H44Cl2N8O2S4 Inv Status: Custom Synthesis

Chemical Name: N1,N2-Bis(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)oxalamide

Avatrombopag Isopropyl Ester Impurity

CAT No: CL-AVBG-11 CAS No: NA Mol Wt: 691.7 Mol F: C32H40Cl2N6O3S2 Inv Status: Custom Synthesis

Chemical Name: Isopropyl 1-(3-chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylate

Avatrombopag Methyl Ester Impurity

CAT No: CL-AVBG-12 CAS No: 2489330-90-5 Mol Wt: 663.7 Mol F: C30H36Cl2N6O3S2 Inv Status: Custom Synthesis

Chemical Name: Methyl 1-(3-chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylate

Avatrombopag Impurity 1

CAT No: CL-AVBG-13 CAS No: 2401867-89-6 Mol Wt: 374.5 Mol F: C7H3Br2ClN2S2 Inv Status: Custom Synthesis

Chemical Name: 5-Bromo-4-(5-bromo-4-chlorothiophen-2-yl)thiazol-2-amine

Avatrombopag Impurity 3

CAT No: CL-AVBG-15 CAS No: 81216-84-4 Mol Wt: 261.2 Mol F: C7H5BrN2S2 Inv Status: Custom Synthesis

Chemical Name: 5-Bromo-4-(thiophen-2-yl)thiazol-2-amine

Avatrombopag Impurity 4

CAT No: CL-AVBG-16 CAS No: 1268118-96-2 Mol Wt: 295.6 Mol F: C7H4BrClN2S2 Inv Status: Custom Synthesis

Chemical Name: 5-Bromo-4-(5-chlorothiophen-2-yl)thiazol-2-amine

Avatrombopag Impurity 5

CAT No: CL-AVBG-17 CAS No: NA Mol Wt: 684.1 Mol F: C29H33Cl3N6O3S2 Inv Status: Custom Synthesis

Chemical Name: 1-(3-Chloro-5-((5-(4-cyclohexylpiperazin-1-yl)-4-(4,5-dichlorothiophen-2-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid

Avatrombopag Impurity 6

CAT No: CL-AVBG-18 CAS No: NA Mol Wt: 615.2 Mol F: C29H35ClN6O3S2 Inv Status: Custom Synthesis

Chemical Name: 1-(3-Chloro-5-((5-(4-cyclohexylpiperazin-1-yl)-4-(thiophen-2-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid

Avatrombopag Impurity 7

CAT No: CL-AVBG-19 CAS No: NA Mol Wt: 760.8 Mol F: C35H43Cl2N7O4S2 Inv Status: Custom Synthesis

Chemical Name: 1-(1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carbonyl)piperidine-4-carboxylic acid

Avatrombopag Impurity 8

CAT No: CL-AVBG-20 CAS No: 2626934-45-8 Mol Wt: 565.6 Mol F: C25H30Cl2N6OS2 Inv Status: Custom Synthesis

Chemical Name: 5-Chloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)-6-(dimethylamino)nicotinamide

Avatrombopag Impurity 9

CAT No: CL-AVBG-21 CAS No: 570407-10-2 Mol Wt: 216.7 Mol F: C7H5ClN2S2 Inv Status: Custom Synthesis

Chemical Name: 4-(4-Chlorothiophen-2-yl)thiazol-2-amine

Avatrombopag Impurity 10

CAT No: CL-AVBG-22 CAS No: 123971-45-9 Mol Wt: 216.7 Mol F: C7H5ClN2S2 Inv Status: Custom Synthesis

Chemical Name: 4-(5-Chlorothiophen-2-yl)thiazol-2-amine

Avatrombopag Impurity 11

CAT No: CL-AVBG-23 CAS No: 339114-12-4 Mol Wt: 216.7 Mol F: C7H5ClN2S2 Inv Status: Custom Synthesis

Chemical Name: 4-(3-Chlorothiophen-2-yl)thiazol-2-amine

Avatrombopag Impurity 12

CAT No: CL-AVBG-24 CAS No: 570407-42-0 Mol Wt: 383 Mol F: C17H23ClN4S2 Inv Status: Custom Synthesis

Chemical Name: 4-(4-Chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine

Avatrombopag Impurity 13

CAT No: CL-AVBG-25 CAS No: 2883585-23-5 Mol Wt: 461.9 Mol F: C17H22BrClN4S2 Inv Status: Custom Synthesis

Chemical Name: 4-(5-Bromo-4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine

Avatrombopag Impurity 14

CAT No: CL-AVBG-26 CAS No: NA Mol Wt: 653.64 Mol F: C28H34Cl2N6O4S2 Inv Status: Custom Synthesis

Chemical Name: 4-(2-(6-(4-carboxypiperidin-1-yl)-5-chloronicotinamido)-4-(4-chlorothiophen-2-yl)thiazol-5-yl)-1-(pentan-2-yl)piperazine 1-oxide

Avatrombopag Impurity 15

CAT No: CL-AVBG-27 CAS No: 57681-59-1 Mol Wt: 195.1 Mol F: C6H4Cl2OS Inv Status: Custom Synthesis

Chemical Name: 1-(4,5-Dichlorothiophen-2-yl)ethan-1-one

Avatrombopag Impurity 16

CAT No: CL-AVBG-28 CAS No: 677007-73-7 Mol Wt: 239.5 Mol F: C6H4BrClOS Inv Status: Custom Synthesis

Chemical Name: 2-Bromo-1-(4-chlorothiophen-2-yl)ethan-1-one

Avatrombopag Impurity 17

CAT No: CL-AVBG-29 CAS No: NA Mol Wt: 318.4 Mol F: C6H3Br2ClOS Inv Status: Custom Synthesis

Chemical Name: 2,2-Dibromo-1-(4-chlorothiophen-2-yl)ethan-1-one

Avatrombopag Impurity 20

CAT No: CL-AVBG-30 CAS No: 1290121-24-2 Mol Wt: 694.1 Mol F: C29H34BrClN6O3S2 Inv Status: Custom Synthesis

Chemical Name: 1-(3-Bromo-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid

Avatrombopag Impurity 2

CAT No: CL-AVBG-31 CAS No: NA Mol Wt: 300.8 Mol F: C11H13ClN4S2 Inv Status: In Stock

Chemical Name: 4-(4-Chlorothiophen-2-yl)-5-(piperazin-1-yl)thiazol-2-amine

Avatrombopag Impurity 27

CAT No: CL-AVBG-32 CAS No: 931395-73-2 Mol Wt: 312.75 Mol F: C14H17ClN2O4 Inv Status: In Stock

Chemical Name: 5-Chloro-6-(4-(ethoxycarbonyl)piperidin-1-yl)nicotinic acid

Type:Impurity Reference Standard

Total Products: 31

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