Amitriptyline is a tricyclic antidepressant used to treat depression, chronic pain, migraines, and neuropathic pain. It works by inhibiting the reuptake of serotonin and norepinephrine in the brain. Its sedative effects are useful for insomnia associated with depression. Side effects include dry mouth, constipation, and cardiac arrhythmias in overdose.
Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Amitriptyline and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Amitriptyline impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Amitriptyline-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.
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