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Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Alvimopan and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Alvimopan impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Alvimopan-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

Alvimopan Dihydrate

CAT No: CL-AVM-01 CAS No: 170098-38-1 Mol Wt: 424.5 : 2(18.0) Mol F: C25H32N2O4 : 2(H2O) Inv Status: Custom Synthesis

Chemical Name: ((S)-2-Benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoyl)glycine dihydrate

Alvimopan Sulfate

CAT No: CL-AVM-02 CAS No: NA Mol Wt: 504.6 Mol F: C25H32N2O7S Inv Status: Custom Synthesis

Chemical Name: ((S)-2-Benzyl-3-((3R,4R)-3,4-dimethyl-4-(3-(sulfooxy)phenyl)piperidin-1-yl)propanoyl)glycine

Alvimopan Acyl Glucuronide

CAT No: CL-AVM-03 CAS No: 1260616-95-2 Mol Wt: 600.7 Mol F: C31H40N2O10 Inv Status: Custom Synthesis

Chemical Name: (2S,3S,4S,5R,6S)-6-((((S)-2-Benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoyl)glycyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

Alvimopan Phenolic Glucuronide

CAT No: CL-AVM-04 CAS No: NA Mol Wt: 600.7 Mol F: C31H40N2O10 Inv Status: Custom Synthesis

Chemical Name: (2S,3S,4S,5R,6S)-6-(3-((3R,4R)-1-((S)-2-Benzyl-3-((carboxymethyl)amino)-3-oxopropyl)-3,4-dimethylpiperidin-4-yl)phenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

Alvimopan Isomer (2R, 3R, 4R)

CAT No: CL-AVM-06 CAS No: 342639-35-4 Mol Wt: 424.5 Mol F: C25H32N2O4 Inv Status: Custom Synthesis

Chemical Name: ((R)-2-Benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoyl)glycine

Alvimopan Isomer (2R, 3S, 4S)

CAT No: CL-AVM-07 CAS No: 156130-44-8 Mol Wt: 424.5 Mol F: C25H32N2O4 Inv Status: Custom Synthesis

Chemical Name: ((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoyl)glycine

Alvimopan Isomer (2S, 3S, 4S)

CAT No: CL-AVM-08 CAS No: 2280857-23-8 Mol Wt: 424.5 Mol F: C25H32N2O4 Inv Status: Custom Synthesis

Chemical Name: ((S)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoyl)glycine

Alvimopan Impurity 1

CAT No: CL-AVM-09 CAS No: 170098-41-6 Mol Wt: 381.5 Mol F: C24H31NO3 Inv Status: Custom Synthesis

Chemical Name: Methyl (R)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoate

Alvimopan Impurity 2

CAT No: CL-AVM-10 CAS No: NA Mol Wt: 381.5 Mol F: C24H31NO3 Inv Status: Custom Synthesis

Chemical Name: Methyl (S)-2-benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoate

Alvimopan Impurity 3

CAT No: CL-AVM-11 CAS No: NA Mol Wt: 381.5 Mol F: C24H31NO3 Inv Status: Custom Synthesis

Chemical Name: Methyl (R)-2-benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoate

Alvimopan Impurity 4

CAT No: CL-AVM-12 CAS No: NA Mol Wt: 339.5 Mol F: C24H29NO3 Inv Status: Custom Synthesis

Chemical Name: Methyl (S)-2-benzyl-3-((3R,4S)-4-(3-hydroxyphenyl)-3,4-dimethyl-3,4-dihydropyridin-1(2H)-yl)propanoate

Alvimopan Impurity 5

CAT No: CL-AVM-13 CAS No: NA Mol Wt: 377.5 Mol F: C24H27NO3 Inv Status: Custom Synthesis

Chemical Name: Methyl (E)-2-(((3R,4S)-4-(3-hydroxyphenyl)-3,4-dimethyl-3,4-dihydropyridin-1(2H)-yl)methyl)-3-phenylacrylate

Alvimopan Impurity 6

CAT No: CL-AVM-14 CAS No: 1420933-63-6 Mol Wt: 379.5 Mol F: C24H29NO3 Inv Status: Custom Synthesis

Chemical Name: Methyl (E)-2-(((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)methyl)-3-phenylacrylate

Alvimopan Impurity 7

CAT No: CL-AVM-15 CAS No: 170098-29-0 Mol Wt: 381.5 Mol F: C24H31NO3 Inv Status: Custom Synthesis

Chemical Name: Methyl (S)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoate

Alvimopan Impurity 8

CAT No: CL-AVM-16 CAS No: 660848-91-9 Mol Wt: 452.6 Mol F: C27H36N2O4 Inv Status: Custom Synthesis

Chemical Name: Ethyl ((S)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoyl)glycinate

Alvimopan Impurity 9

CAT No: CL-AVM-17 CAS No: NA Mol Wt: 217.3 Mol F: C14H19NO Inv Status: Custom Synthesis

Chemical Name: 3-(1,3,6-Trimethyl-1,2,3,6-tetrahydropyridin-4-yl)phenol

Alvimopan Impurity 10

CAT No: CL-AVM-18 CAS No: NA Mol Wt: 217.3 Mol F: C14H19NO Inv Status: Custom Synthesis

Chemical Name: 3-(1,3,5-Trimethyl-1,2,3,6-tetrahydropyridin-4-yl)phenol

Alvimopan Impurity 11

CAT No: CL-AVM-19 CAS No: 2250243-53-7 Mol Wt: 217.3 Mol F: C14H19NO Inv Status: Custom Synthesis

Chemical Name: 3-(1,3,3-Trimethyl-1,2,3,6-tetrahydropyridin-4-yl)phenol

Alvimopan Impurity 12

CAT No: CL-AVM-20 CAS No: 1980007-99-5 Mol Wt: 205.3 Mol F: C13H19NO Inv Status: Custom Synthesis

Chemical Name: 3-((3R,4S)-3,4-Dimethylpiperidin-4-yl)phenol

Alvimopan Impurity Mixture 1

CAT No: CL-AVM-22 CAS No: NA Mol Wt: 849.1 Mol F: C50H64N4O8 Inv Status: Custom Synthesis

Chemical Name: ((R)-2-Benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoyl)glycine compound with ((R)-2-benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoyl)glycine (1:1)

Alvimopan Impurity Mixture 2

CAT No: CL-AVM-23 CAS No: NA Mol Wt: 849.1 Mol F: C50H64N4O8 Inv Status: Custom Synthesis

Chemical Name: ((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoyl)glycine compound with ((S)-2-benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoyl)glycine (1:1)

Alvimopan Impurity 14

CAT No: CL-AVM-24 CAS No: 76932-18-8 Mol Wt: 219.2 Mol F: C12H13NO3 Inv Status: Custom Synthesis

Chemical Name: (2-Benzylacryloyl)glycine

Alvimopan Impurity 15

CAT No: CL-AVM-25 CAS No: 156130-41-5 Mol Wt: 367.5 Mol F: C23H29NO3 Inv Status: Custom Synthesis

Chemical Name: (S)-2-Benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoic acid

Alvimopan Impurity 16

CAT No: CL-AVM-26 CAS No: NA Mol Wt: 438.6 Mol F: C26H34N2O4 Inv Status: Custom Synthesis

Chemical Name: Methyl ((R)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoyl)glycinate

Alvimopan Impurity 17

CAT No: CL-AVM-27 CAS No: NA Mol Wt: 251.3 Mol F: C13H17NO4 Inv Status: Custom Synthesis

Chemical Name: Methyl (R)-(2-benzyl-3-hydroxypropanoyl)glycinate

Alvimopan Impurity 18

CAT No: CL-AVM-28 CAS No: 145340-45-0 Mol Wt: 259.4 Mol F: C17H25NO Inv Status: Custom Synthesis

Chemical Name: 4-(3-Isopropoxyphenyl)-1,3,4-trimethyl-1,2,3,4-tetrahydropyridine

Alvimopan Impurity 19

CAT No: CL-AVM-29 CAS No: 1314751-85-3 Mol Wt: 343.4 Mol F: C15H21NO6S Inv Status: Custom Synthesis

Chemical Name: Ethyl (S)-(2-benzyl-3-((methylsulfonyl)oxy)propanoyl)glycinate

Alvimopan Impurity 20

CAT No: CL-AVM-30 CAS No: 1314751-83-1 Mol Wt: 265.3 Mol F: C14H19NO4 Inv Status: Custom Synthesis

Chemical Name: Ethyl-2-[(2S)-2-benzyl-3-hydroxy propanamido]acetate

Alvimopan Impurity 21

CAT No: CL-AVM-31 CAS No: 660848-81-7 Mol Wt: 247.3 Mol F: C14H17NO3 Inv Status: Custom Synthesis

Chemical Name: Ethyl (2-benzylacryloyl)glycinate

Alvimopan Impurity 22

CAT No: CL-AVM-32 CAS No: 1852472-89-9 Mol Wt: 315.3 Mol F: C13H17NO6S Inv Status: Custom Synthesis

Chemical Name: 2-[(2S)-2-Benzyl-3-(methanesulfonyloxy) propanamido ] acetic acid

Alvimopan Impurity 23

CAT No: CL-AVM-33 CAS No: 1314751-81-9 Mol Wt: 355.4 Mol F: C21H25NO4 Inv Status: Custom Synthesis

Chemical Name: Ethyl (S)-(2-benzyl-3-(benzyloxy)propanoyl)glycinate

Alvimopan Impurity 24

CAT No: CL-AVM-34 CAS No: 1237735-54-4 Mol Wt: 270.3 Mol F: C17H18O3 Inv Status: Custom Synthesis

Chemical Name: (S)-2-Benzyl-3-(benzyloxy)propanoic acid

Alvimopan Impurity 25

CAT No: CL-AVM-35 CAS No: 2184736-45-4 Mol Wt: 343.4 Mol F: C15H21NO6S Inv Status: Custom Synthesis

Chemical Name: Ethyl (R)-(2-benzyl-3-((methylsulfonyl)oxy)propanoyl)glycinate

Alvimopan Impurity 27

CAT No: CL-AVM-37 CAS No: 119193-19-0 Mol Wt: 205.3 Mol F: C13H19NO Inv Status: Custom Synthesis

Chemical Name: 3-((3R,4R)-3,4-Dimethylpiperidin-4-yl)phenol

Alvimopan Impurity 28

CAT No: CL-AVM-38 CAS No: 145678-87-1 Mol Wt: 205.3 Mol F: C13H19NO Inv Status: Custom Synthesis

Chemical Name: 3-((3S,4S)-3,4-Dimethylpiperidin-4-yl)phenol

Alvimopan Impurity 13

CAT No: CL-AVM-39 CAS No: 2165896-76-2 Mol Wt: 205.3 Mol F: C13H19NO Inv Status: Custom Synthesis

Chemical Name: 3-((3S,4R)-3,4-Dimethylpiperidin-4-yl)phenol

Alvimopan Impurity 29

CAT No: CL-AVM-40 CAS No: NA Mol Wt: 284.2 Mol F: C13H18BrNO Inv Status: Custom Synthesis

Chemical Name: 2-Bromo-5-(3R,4R)-3,4-dimethylpiperidin-4yl-phenol

Alvimopan Impurity 30

CAT No: CL-AVM-41 CAS No: 156130-37-9 Mol Wt: 367.5 Mol F: C23H29NO3 Inv Status: Custom Synthesis

Chemical Name: (R)-2-Benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoic acid

Alvimopan Impurity 31

CAT No: CL-AVM-42 CAS No: 660848-93-1 Mol Wt: 452.6 Mol F: C27H36N2O4 Inv Status: Custom Synthesis

Chemical Name: Ethyl ((R)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoyl)glycinate

Alvimopan Impurity 32

CAT No: CL-AVM-43 CAS No: 1527494-97-8 Mol Wt: 127.2 : 386.4 Mol F: C7H13NO : C20H18O8 Inv Status: Custom Synthesis

Chemical Name: (S)-1,3-dimethylpiperidin-4-one (2R,3R)-2,3-bis((4-methylbenzoyl)oxy)succinate

Alvimopan Impurity 33

CAT No: CL-AVM-44 CAS No: NA Mol Wt: 127.2 : 386.4 Mol F: C7H13NO : C20H18O8 Inv Status: Custom Synthesis

Chemical Name: (R)-1,3-dimethylpiperidin-4-one (2S,3S)-2,3-bis((4-methylbenzoyl)oxy)succinate

Alvimopan D7

CAT No: CL-AVM-45 CAS No: 1261396-48-8 Mol Wt: 431.6 Mol F: C25H25D7N2O4 Inv Status: Custom Synthesis

Chemical Name: ((S)-2-(((3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)methyl)-3-(phenyl-d5)propanoyl-3,3-d2)glycine

Type:Impurity Reference Standard

Total Products: 42

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