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Adapalene is a topical retinoid used for the treatment of acne vulgaris. It works by modulating cell differentiation and keratinization, helping to prevent comedone formation. It has anti-inflammatory properties and is less irritating than older retinoids like tretinoin. Adapalene is available over-the-counter in many countries.
Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Adapalene and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Adapalene impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Adapalene-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

CAT No: CL-ADPL-01
CAS No: NA
Mol Wt: 412.5
Mol F: C28H28O3
Inv Status:Custom Synthesis
CAT No: CL-ADPL-02
CAS No: 932033-58-4
Mol Wt: 342.3
Mol F: C22H14O4
Inv Status:In Stock
CAT No: CL-ADPL-03
CAS No: 1346599-76-5
Mol Wt: 428.5
Mol F: C28H28O4
Inv Status:Custom Synthesis
CAT No: CL-ADPL-04
CAS No:  43109-77-9
Mol Wt: 242.4
Mol F: C17H22O
Inv Status:Custom Synthesis
CAT No: CL-ADPL-05
CAS No:  932033-57-3
Mol Wt: 482.7
Mol F: C34H42O2
Inv Status:Custom Synthesis
CAT No: CL-ADPL-06
CAS No: 106685-41-0
Mol Wt: 426.5
Mol F: C29H30O3
Inv Status:Custom Synthesis
CAT No: CL-ADPL-07
CAS No: 125316-60-1
Mol Wt: 398.5
Mol F: C27H26O3
Inv Status:Custom Synthesis
CAT No: CL-ADPL-08
CAS No: 104224-63-7
Mol Wt: 321.2
Mol F: C17H21BrO
Inv Status:Custom Synthesis
CAT No: CL-ADPL-09
CAS No: NA
Mol Wt: 688.8
Mol F: C46H40O6
Inv Status:Custom Synthesis
CAT No: CL-ADPL-10
CAS No: 132292-17-2
Mol Wt: 278.3
Mol F: C18H14O3
Inv Status:Custom Synthesis
CAT No: CL-ADPL-11
CAS No: 33626-98-1
Mol Wt: 265.1
Mol F: C12H9BrO2
Inv Status:In Stock
CAT No: CL-ADPL-12
CAS No: 104224-68-2
Mol Wt: 307.2
Mol F: C16H19BrO
Inv Status:Custom Synthesis
CAT No: CL-ADPL-13
CAS No: 93-09-4
Mol Wt: 172.2
Mol F: C11H8O2
Inv Status:Custom Synthesis
CAT No: CL-ADPL-14
CAS No: 5773-80-8
Mol Wt: 251.1
Mol F: C11H7BrO2
Inv Status:Custom Synthesis
CAT No: CL-ADPL-15
CAS No: NA
Mol Wt: 442.6
Mol F: C29H30O4
Inv Status:Custom Synthesis
CAT No: CL-ADPL-16
CAS No: 28996-06-7
Mol Wt: 168.2
Mol F: C10H16O2
Inv Status:Custom Synthesis
CAT No: CL-ADPL-17
CAS No: 93353-67-4
Mol Wt: 265.1
Mol F: C12H9BrO2
Inv Status:Custom Synthesis
CAT No: CL-ADPL-18
CAS No: 2459-25-8
Mol Wt: 186.2
Mol F: C12H10O2
Inv Status:Custom Synthesis
CAT No: CL-ADPL-19
CAS No: 161912-38-5
Mol Wt: 370.4
Mol F: C24H18O4
Inv Status:Custom Synthesis
CAT No: CL-ADPL-20
CAS No: 100751-63-1
Mol Wt: 237.1
Mol F: C11H9BrO
Inv Status:Custom Synthesis
CAT No: CL-ADPL-21
CAS No: NA
Mol Wt: 442.5
Mol F: C28H26O5
Inv Status:Custom Synthesis
CAT No: CL-ADPL-22
CAS No: NA
Mol Wt: 400.5
Mol F: C27H28O3
Inv Status:Custom Synthesis
CAT No: CL-ADPL-23
CAS No: 128272-36-6
Mol Wt: 292.3
Mol F: C19H16O3
Inv Status:Custom Synthesis
CAT No: CL-ADPL-24
CAS No: 106685-43-2
Mol Wt: 412.5
Mol F: C28H28O3
Inv Status:Custom Synthesis
CAT No: CL-ADPL-25
CAS No: 107430-57-9
Mol Wt: 278.3
Mol F: C18H14O3
Inv Status:Custom Synthesis
CAT No: CL-ADPL-26
CAS No: 7314-85-4
Mol Wt: 215.1
Mol F: C10H15Br
Inv Status:Custom Synthesis
CAT No: CL-ADPL-27
CAS No: NA
Mol Wt: 321.3
Mol F: C17H21BrO
Inv Status:Custom Synthesis
CAT No: CL-ADPL-28
CAS No: NA
Mol Wt: 611.6
Mol F: C36H35BrO4
Inv Status:Custom Synthesis
CAT No: CL-ADPL-29
CAS No: 932033-56-2
Mol Wt: 506.3
Mol F: C24H26Br2O2
Inv Status:Custom Synthesis
CAT No: CL-ADPL-30
CAS No: 1276433-89-6
Mol Wt: 415.6
Mol F: C28H25D3O3
Inv Status:Custom Synthesis
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