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Tapentadol is a centrally acting analgesic that combines opioid receptor agonism with norepinephrine reuptake inhibition, offering effective pain relief. It is used to manage moderate to severe pain, including neuropathic pain associated with diabetic peripheral neuropathy. The dual mechanism provides both opioid-like and antidepressant-like effects, enhancing its efficacy in pain management.
Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Tapentadol and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Tapentadol impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Tapentadol-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

CAT No: CL-TPD-NO-01
CAS No: NA
Mol Wt: 236.32
Mol F:  C13H20N2O2
Inv Status:Custom Synthesis
CAT No: CL-TPD-NO-02
CAS No: NA
Mol Wt: 234.3
Mol F: C13H18N2O2
Inv Status:Custom Synthesis
CAT No: CL-TPD-NO-03
CAS No: NA
Mol Wt: 234.3
Mol F: C13H18N2O2
Inv Status:Custom Synthesis
CAT No: CL-TPD-NO-003
CAS No: NA
Mol Wt: 250.34
Mol F: C14H22N2O2
Inv Status:Custom Synthesis
CAT No: CL-TPD-NO-04
CAS No: NA
Mol Wt: 316.37
Mol F: C13H20N2O5S
Inv Status:Custom Synthesis
CAT No: CL-TPD-NO-05
CAS No: NA
Mol Wt: 236.32
Mol F: C13H20N2O2
Inv Status:Custom Synthesis
CAT No: CL-TPD-NO-06
CAS No: NA
Mol Wt: 236.27
Mol F: C12H16N2O3
Inv Status:Custom Synthesis
CAT No: CL-TPD-NO-07
CAS No: NA
Mol Wt: 266.34
Mol F: C14H22N2O3
Inv Status:Custom Synthesis
CAT No: CL-TPD-NO-08
CAS No: NA
Mol Wt: 250.34
Mol F: C14H22N2O2
Inv Status:Custom Synthesis
CAT No: CL-TPD-NO-09
CAS No: NA
Mol Wt: 236.27
Mol F: C13H20N2O2
Inv Status:Custom Synthesis
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