A neprilysin inhibitor used in combination with valsartan to treat heart failure with reduced ejection fraction. By inhibiting neprilysin, it increases levels of natriuretic peptides, which help reduce blood pressure and fluid overload. This combination therapy reduces the risk of cardiovascular death and hospitalizations related to heart failure.
Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Sacubitril and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Sacubitril impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Sacubitril-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.
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