Levomefolate, or L-methylfolate, is the biologically active form of folate used in the treatment of folate deficiency, depression, and certain cardiovascular conditions. Unlike folic acid, it does not require conversion by the MTHFR enzyme, making it suitable for individuals with MTHFR polymorphisms. It supports neurotransmitter synthesis and homocysteine metabolism. It is often combined with antidepressants.
Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Levomefolate and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Levomefolate impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Levomefolate-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.
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