Talazoparib is a potent poly(ADP-ribose) polymerase (PARP) inhibitor that disrupts DNA repair mechanisms in cancer cells, leading to cell death. It is used in the treatment of certain cancers, including BRCA-mutated breast cancer. Its dual mechanism of PARP trapping and catalytic inhibition makes it especially effective in targeting tumors with deficient DNA repair pathways.
Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Talazoparib and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Talazoparib impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Talazoparib-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.