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Ponatinib is a tyrosine kinase inhibitor used to treat chronic myelogenous leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). It works by blocking abnormal proteins caused by the Philadelphia chromosome, which contributes to cancer cell growth. Ponatinib is often used when other treatments have failed or when the cancer is resistant to other therapies.
Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Ponatinib and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Ponatinib impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Ponatinib-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

CAT No: CL-PON-01
CAS No: 943319-70-8
Mol Wt: 532.6
Mol F: C29H27F3N6O
Inv Status:Custom Synthesis
CAT No: CL-PON-02
CAS No: 943319-87-7
Mol Wt: 518.5
Mol F: C28H25F3N6O
Inv Status:Custom Synthesis
CAT No: CL-PON-03
CAS No: 2227480-51-3
Mol Wt: 548.6
Mol F: C29H27F3N6O2
Inv Status:Custom Synthesis
CAT No: CL-PON-04
CAS No: 2097674-16-1
Mol Wt: 828.9
Mol F: C46H46F6N6O2
Inv Status:Custom Synthesis
CAT No: CL-PON-05
CAS No: 1562993-37-6
Mol Wt: 540.6
Mol F: C29H19D8F3N6O
Inv Status:Custom Synthesis
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