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Difamilast is a topical phosphodiesterase-4 inhibitor used to treat atopic dermatitis. It reduces inflammation and itching by modulating cytokine production. It is applied directly to the skin and has minimal systemic absorption.
Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Difamilast and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Difamilast impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Difamilast-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.

CAT No: CL-DFML-01
CAS No: 937782-05-3
Mol Wt: 446.5
Mol F: C23H24F2N2O5
Inv Status:Custom Synthesis
CAT No: CL-DFML-02
CAS No: 221699-45-2
Mol Wt: 238.3
Mol F: C13H18O4
Inv Status:Custom Synthesis
CAT No: CL-DFML-03
CAS No: NA
Mol Wt: 253.2
Mol F: C9H7F4NO3
Inv Status:Custom Synthesis
CAT No: CL-DFML-04
CAS No: 1369817-11-7
Mol Wt: 237.3
Mol F: C13H19NO3
Inv Status:Custom Synthesis
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