Cilastatin is a drug used in combination with imipenem (a broad-spectrum antibiotic) to treat bacterial infections. Cilastatin inhibits the breakdown of imipenem in the kidneys, thus enhancing its effectiveness. The combination of cilastatin and imipenem is particularly useful in treating serious infections, such as those caused by multidrug-resistant organisms. Side effects may include gastrointestinal upset, skin rashes, and changes in liver function tests.
Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Cilastatin and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Cilastatin impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Cilastatin-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.
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