Aprepitant is a neurokinin-1 (NK1) receptor antagonist used to prevent nausea and vomiting caused by chemotherapy and surgery. It is usually used in combination with other antiemetics like 5-HT3 antagonists and corticosteroids. It is available orally and intravenously. It is well-tolerated and effective for delayed nausea.
Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Aprepitant and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Aprepitant impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Aprepitant-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.