Colistimethate is an antibiotic used to treat infections caused by multidrug-resistant Gram-negative bacteria, particularly Pseudomonas aeruginosa. It works by disrupting the bacterial cell membrane, leading to cell death. Colistimethate is often used in hospital settings, particularly for treating infections in patients with cystic fibrosis or those in intensive care units. Potential side effects include nephrotoxicity (kidney damage) and neurotoxicity, including dizziness and tingling sensations.
Cleanchem is a trusted provider of premium pharmaceutical reference materials, specializing in Colistimethate and its associated compounds. Our catalog includes pharmacopeial and non-pharmacopeial Colistimethate impurities, metabolites, nitrosamine derivatives (N-NO compounds), and stable isotope-labeled products. These reference standards play a critical role in pharmaceutical R&D, supporting activities such as product formulation, ANDA and DMF submissions, quality assurance, analytical method development, and stability assessments.
All Colistimethate-related substances undergo comprehensive characterization and are delivered with complete Certificates of Analysis and supporting analytical documentation to ensure regulatory adherence. Upon request, we can offer EP/USP traceable standards. Our products are routinely re-evaluated to maintain consistent quality and performance.
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